T helper cytokine patterns: defined subsets, random expression, and external modulation (Q34939023)

5 August 2017

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title

T helper cytokine patterns: defined subsets, random expression, and external modulation (English)

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5 August 2017

Tim R Mosmann

1

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5 August 2017

James J Kobie

series ordinal

2

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5 August 2017

F Eun-Hyung Lee

series ordinal

3

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5 August 2017

Sally A Quataert

series ordinal

4

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5 August 2017

publication date

6 February 2009

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5 August 2017

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5 August 2017

volume

45

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5 August 2017

issue

2-3

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5 August 2017

page(s)

173-184

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Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells.

5 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS12026-009-8098-5

CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8098-5

T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8098-5

Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8098-5

Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15--the Amplispot assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8098-5

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

21 January 2018

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12 December 2020

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

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12 December 2020

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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12 December 2020

Simultaneous Th1-type cytokine expression is a signature of peritoneal CD4+ lymphocytes responding to infection with Listeria monocytogenes

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12 December 2020

Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells.

1 reference

12 December 2020

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

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12 December 2020

Signaling pathways in Th2 development

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12 December 2020

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

12 December 2020

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

1 reference

12 December 2020

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

1 reference

12 December 2020

Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

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12 December 2020

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

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12 December 2020

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

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12 December 2020

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

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12 December 2020

IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.

1 reference

12 December 2020

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies

1 reference

12 December 2020

A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines

1 reference

12 December 2020

The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects.

1 reference

12 December 2020

Heterogeneity of single cell cytokine gene expression in clonal T cell populations

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12 December 2020

In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells

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12 December 2020

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

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12 December 2020

Intracellular cytokine optimization and standard operating procedure

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12 December 2020

Arrested differentiation, the self-renewing memory lymphocyte, and vaccination.

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12 December 2020

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells

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12 December 2020

Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion

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12 December 2020

IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays

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12 December 2020

PU.1 expression delineates heterogeneity in primary Th2 cells.

1 reference

12 December 2020

Generation, persistence, and modulation of Th0 effector cells: role of autocrine IL-4 and IFN-gamma.

1 reference

12 December 2020

Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype

1 reference

12 December 2020

Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like responsein vivo

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12 December 2020

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

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12 December 2020

A model of immune regulation as a consequence of randomized lymphocyte division and death times

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12 December 2020

Human atopen-specific types 1 and 2 T helper cell clones

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12 December 2020

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

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12 December 2020

Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions

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12 December 2020

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

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12 December 2020

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones

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12 December 2020

Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype

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12 December 2020

Amphiregulin, a TH2 cytokine enhancing resistance to nematodes

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12 December 2020

Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity

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12 December 2020

CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases.

1 reference

12 December 2020

The lineage decisions of helper T cells

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12 December 2020

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

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12 December 2020

Functional diversity of helper T lymphocytes

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12 December 2020

Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites.

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12 December 2020

Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells

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12 December 2020

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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12 December 2020

Molecular mechanisms regulating Th1 immune responses

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12 December 2020

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

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12 December 2020

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones

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12 December 2020

Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Lineage relationship and protective immunity of memory CD8 T cell subsets

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12 December 2020

Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix

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12 December 2020

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

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12 December 2020

10.1007/S12026-009-8098-5

Identifiers

DOI

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Dimensions Publication ID

5 August 2017

1040189574

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