Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus (Q34940029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19202064%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus (English)

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3

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author name string

Alexandros Tzatsos

series ordinal

1

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21 January 2020

Raymond Pfau

series ordinal

2

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21 January 2020

Philip N Tsichlis

series ordinal

4

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21 January 2020

language of work or name

English

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publication date

6 February 2009

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Proceedings of the National Academy of Sciences of the United States of America

21 January 2020

published in

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21 January 2020

volume

106

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21 January 2020

issue

8

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21 January 2020

page(s)

2641-2646

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The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress

21 January 2020

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Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

8 July 2018

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Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation

8 July 2018

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Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila

8 July 2018

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JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

8 July 2018

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Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

8 July 2018

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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

8 July 2018

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Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor

8 July 2018

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Polycomb silencing mechanisms and the management of genomic programmes

8 July 2018

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Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences

8 July 2018

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Polycomb silencers control cell fate, development and cancer

8 July 2018

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Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets

8 July 2018

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

8 July 2018

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

8 July 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

8 July 2018

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Leaving a mark: the many footprints of the elongating RNA polymerase II.

8 July 2018

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Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation

8 July 2018

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Histone demethylation by a family of JmjC domain-containing proteins

8 July 2018

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Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1

8 July 2018

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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

8 July 2018

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Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

8 July 2018

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INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

8 July 2018

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650317

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650317

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650317

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813139106

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813139106

Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813139106

High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0813139106

21 January 2018

Identifiers

DOI

10.1073/PNAS.0813139106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19202064%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19202064%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference