Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole. (Q34940421)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709346%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709346%20AND%20SRC:MED&resulttype=core&format=json

ABC multidrug transporter

2 November 2019

main subject

Aspergillus fumigatus

0 references

1 reference

GeneDB

Putative multidrug resistance protein

5 February 2019

1 reference

GeneDB

14-alpha sterol demethylase

6 February 2019

1 reference

6 February 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709346%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Adriana M Nascimento

1

1 reference

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2 November 2019

Steven Park

3

1 reference

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2 November 2019

Salvatore A E Marras

4

1 reference

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2 November 2019

Guillaume Delmas

5

1 reference

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2 November 2019

Uma Oza

6

1 reference

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2 November 2019

Karen Lolans

7

1 reference

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2 November 2019

Michael N Dudley

8

1 reference

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2 November 2019

Paul A Mann

9

1 reference

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2 November 2019

David S Perlin

10

1 reference

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2 November 2019

language of work or name

English

0 references

publication date

1 May 2003

1 reference

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Antimicrobial Agents and Chemotherapy

2 November 2019

published in

1 reference

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2 November 2019

volume

47

1 reference

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2 November 2019

issue

5

1 reference

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2 November 2019

page(s)

1719-1726

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Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase

2 November 2019

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1 reference

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Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.

8 July 2018

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8 July 2018

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8 July 2018

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The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network

8 July 2018

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8 July 2018

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8 July 2018

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Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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26 October 2018

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26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12709346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduced susceptibility in laboratory-selected mutants of Aspergillus fumigatus to itraconazole due to decreased intracellular accumulation of the antifungal agent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12709346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.47.5.1719-1726.2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709346%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709346%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference