Identification of a pH sensor in the furin propeptide that regulates enzyme activation (Q34940590)

5 August 2017

Identification of a pH sensor in the furin propeptide that regulates enzyme activation (English)

1 reference

5 August 2017

Sylvain F Feliciangeli

1

1 reference

5 August 2017

Laurel Thomas

2

1 reference

5 August 2017

Gregory K Scott

3

1 reference

5 August 2017

Ezhilkani Subbian

4

1 reference

5 August 2017

Chien-Hui Hung

5

1 reference

5 August 2017

Sean S Molloy

6

1 reference

5 August 2017

François Jean

7

1 reference

5 August 2017

Ujwal Shinde

8

1 reference

5 August 2017

Gary Thomas

9

1 reference

5 August 2017

language of work or name

English

0 references

publication date

6 April 2006

1 reference

Journal of Biological Chemistry

5 August 2017

1 reference

5 August 2017

281

1 reference

5 August 2017

23

1 reference

5 August 2017

16108-16116

1 reference

PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Red blood cell pH, the Bohr effect, and other oxygenation-linked phenomena in blood O2 and CO2 transport

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Identification of furin pro-region determinants involved in folding and activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

SWISS-MODEL: An automated protein homology-modeling server

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The crystal structure of the proprotein processing proteinase furin explains its stringent specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Precursor processing by kex2/furin proteases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Furin at the cutting edge: from protein traffic to embryogenesis and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Functional role of polar amino acid residues in Na+/H+ exchangers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

pH-induced conformational transitions of a molten-globule-like state of the inhibitory prodomain of furin: implications for zymogen activation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Proteolytic processing in the secretory pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Inward rectification in KATP channels: a pH switch in the pore.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 A resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Regulation of endosome sorting by a specific PP2A isoform

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The proprotein convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Aggregation as a determinant of protein fate in post-Golgi compartments: role of the luminal domain of furin in lysosomal targeting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Processing of proopiomelanocortin by insulin secretory granule proinsulin processing endopeptidases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Amino acid, peptide, and protein volume in solution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

The stress response in Chinese hamster ovary cells. Regulation of ERp72 and protein disulfide isomerase expression and secretion.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

Folding pathway mediated by an intramolecular chaperone: intrinsically unstructured propeptide modulates stochastic activation of subtilisin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

Stability and global fold of the mouse prohormone convertase 1 pro-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

Positive selection dictates the choice between kinetic and thermodynamic protein folding and stability in subtilases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

Substrate-induced activation of a trapped IMC-mediated protein folding intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600760200

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293020

Quantitative characterization of furin specificity. Energetics of substrate discrimination using an internally consistent set of hexapeptidyl methylcoumarinamides

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16601116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and characterization of the prohormone convertase PC1(PC3)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16601116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M600760200

1 reference

5 August 2017

1 reference

5 August 2017

1 reference