Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms (Q34946043)

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21 January 2020

title

Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms (English)

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21 January 2020

6

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21 January 2020

author name string

Emmanuel Debrand

1

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21 January 2020

Yasmine El Jai

2

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21 January 2020

Lorraine Spence

3

1 reference

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21 January 2020

Neil Bate

4

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21 January 2020

Uta Praekelt

5

1 reference

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21 January 2020

Susan J Monkley

7

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21 January 2020

David R Critchley

8

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21 January 2020

language of work or name

English

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publication date

7 February 2009

1 reference

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21 January 2020

1 reference

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21 January 2020

volume

276

1 reference

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21 January 2020

issue

6

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21 January 2020

page(s)

1610-1628

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Talin depletion reveals independence of initial cell spreading from integrin activation and traction

21 January 2020

cites work

1 reference

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Structural basis for the autoinhibition of talin in regulating integrin activation

8 July 2018

1 reference

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Analyzing real-time PCR data by the comparative C(T) method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The structure of the C-terminal actin-binding domain of talin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

8 July 2018

1 reference

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Talin is required for integrin-mediated platelet function in hemostasis and thrombosis

8 July 2018

1 reference

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Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes

8 July 2018

1 reference

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MicroRNA expression profile in granulocytes from primary myelofibrosis patients.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

A mammalian microRNA expression atlas based on small RNA library sequencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Computational and transcriptional evidence for microRNAs in the honey bee genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Control of alternative RNA splicing and gene expression by eukaryotic riboswitches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Structural basis of integrin activation by talin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

An essential role for talin during alpha(M)beta(2)-mediated phagocytosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Ectoplasmic specialization: a friend or a foe of spermatogenesis?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Talin2 is induced during striated muscle differentiation and is targeted to stable adhesion complexes in mature muscle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The structure and regulation of vinculin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Structural definition of the F-actin-binding THATCH domain from HIP1R

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The N-terminal half of talin2 is sufficient for mouse development and survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

MatInspector and beyond: promoter analysis based on transcription factor binding sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The implications of structured 5' untranslated regions on translation and disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

A role for talin in presynaptic function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Talin B is required for force transmission in morphogenesis of Dictyostelium.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Extracellular matrix: recent advances on its role in junction dynamics in the seminiferous epithelium during spermatogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

8 July 2018

1 reference

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MicroRNAs: genomics, biogenesis, mechanism, and function

8 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

8 July 2018

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Structure, function and evolution of CpG island promoters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The RNA polymerase II core promoter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

New microRNAs from mouse and human

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Analysis of the mammalian talin2 gene TLN2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Signal transduction and the Ets family of transcription factors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Disruption of the talin gene arrests mouse development at the gastrulation stage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

8 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Gene duplication and functional divergence during evolution of the cytoskeletal linker protein talin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2702505

Characterization of an Actin-binding Site within the Talin FERM Domain

26 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06893.X

Spermatid residual bodies in the mouse as viewed by scanning electron microscopy

21 January 2018

1 reference

12 December 2020

Efficiency assessment of the gene trap approach

1 reference

12 December 2020

Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector

1 reference

12 December 2020

Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis

1 reference

12 December 2020

Talin1 regulates TCR-mediated LFA-1 function

1 reference

12 December 2020

Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1

1 reference

12 December 2020

10.1111/J.1742-4658.2009.06893.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19220457%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19220457%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

19220457

1 reference