Identification of TOR signaling complexes: more TORC for the cell growth engine (Q34952903)

5 August 2017

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title

Identification of TOR signaling complexes: more TORC for the cell growth engine (English)

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Gene Ontology release 2020-05-02

5 August 2017

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Robert T Abraham

1

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PubMed ID

12372295

5 August 2017

language of work or name

English

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publication date

1 October 2002

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5 August 2017

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5 August 2017

111

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5 August 2017

9-12

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5 August 2017

1

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Immunopharmacology of rapamycin

5 August 2017

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Regulation of translation initiation by FRAP/mTOR

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

Identification of a conserved motif required for mTOR signaling

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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2901009-7

7 January 2021

10.1016/S0092-8674(02)01009-7

Identifiers

DOI

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5 August 2017

1 reference

PubMed ID

12372295