New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. (Q34973760)

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27 December 2019

title

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action (English)

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27 December 2019

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Victor M Castillo-Acosta

2

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27 December 2019

Luis Miguel Ruiz-Pérez

10

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27 December 2019

Ian H. Gilbert

12

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Dolores Gonzalez-Pacanowska

27 December 2019

13

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author name string

Ludovic Gros

1

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27 December 2019

Carmen Jiménez Jiménez

3

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27 December 2019

Marco Sealey-Cardona

4

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27 December 2019

Sofia Vargas

5

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27 December 2019

Vanessa Yardley

7

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27 December 2019

Lauren Rattray

8

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27 December 2019

Simon L Croft

9

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27 December 2019

Julio A Urbina

11

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27 December 2019

Antonio Manuel Estévez

6

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language of work or name

English

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publication date

1 August 2006

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Antimicrobial Agents and Chemotherapy

27 December 2019

published in

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27 December 2019

volume

50

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27 December 2019

page(s)

2595-2601

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27 December 2019

issue

8

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Structural analysis of sterol distributions in the plasma membrane of living cells

27 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538673

Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis.

8 July 2018

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Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa

8 July 2018

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Ultrastructural and biochemical alterations induced by 22,26-azasterol, a delta(24(25))-sterol methyltransferase inhibitor, on promastigote and amastigote forms of Leishmania amazonensis.

8 July 2018

1 reference

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Sterol methyl transferase: enzymology and inhibition

8 July 2018

1 reference

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The adaptative mechanisms of Trypanosoma brucei for sterol homeostasis in its different life-cycle environments

8 July 2018

1 reference

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The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

8 July 2018

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Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites

8 July 2018

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The current status of antiparasite chemotherapy

8 July 2018

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Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii

8 July 2018

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Biochemical and physiological effects of sterol alterations in yeast--a review

8 July 2018

1 reference

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Effects of an azasterol inhibitor of sterol 24-transmethylation on sterol biosynthesis and growth of Leishmania donovani promastigotes

8 July 2018

1 reference

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Azasterol inhibition of delta 24-sterol methyltransferase in Saccharomyces cerevisiae

8 July 2018

1 reference

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Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers

8 July 2018

1 reference

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Inhibition of sterol biosynthesis enzymes in vitro by analogues of high-energy carbocationic intermediates

8 July 2018

1 reference

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Evaluation of azasterols as anti-parasitics.

8 July 2018

1 reference

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Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics.

26 October 2018

1 reference

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Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi.

26 October 2018

1 reference

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Antiproliferative effects of delta 24(25) sterol methyl transferase inhibitors on Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies

26 October 2018

1 reference

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TERATOGENIC ACTION OF TRIPARANOL IN ANIMALS

9 December 2018

1 reference

12 December 2020

Exogenous and endogenous sources of sterols in the culture-adapted procyclic trypomastigotes of Trypanosoma brucei

1 reference

12 December 2020

Modification of the sterol composition of Trypanosoma (Schizotrypanum) cruzi epimastigotes by delta 24(25)-sterol methyl transferase inhibitors and their combinations with ketoconazole

1 reference

12 December 2020

Ultrastructural alterations in Trypanosoma (Schizotrypanum) cruzi induced by Delta(24(25)) sterol methyl transferase inhibitors and their combinations with ketoconazole

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.01508-05

1 reference

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27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16870747%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference