Human RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence. (Q34976789)

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1 January 2020

title

Human RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence (English)

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1 January 2020

2

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1 January 2020

Shan-Lu Liu

series ordinal

3

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1 January 2020

author name string

Marceline Côté

series ordinal

1

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language of work or name

English

0 references

publication date

18 June 2007

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Biochemical and Biophysical Research Communications

1 January 2020

published in

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1 January 2020

volume

360

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issue

1

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page(s)

219-225

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Uncoupling ligand-dependent and -independent mechanisms for mitogen-activated protein kinase activation by the murine Ron receptor tyrosine kinase

1 January 2020

cites work

1 reference

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Transformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2

8 July 2018

1 reference

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The normal response to RAS: senescence or transformation?

8 July 2018

1 reference

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Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

8 July 2018

1 reference

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Epithelial-mesenchymal transitions in development and pathologies

8 July 2018

1 reference

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High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts

8 July 2018

1 reference

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

8 July 2018

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Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activation

8 July 2018

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Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase

8 July 2018

1 reference

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Hyaluronidase 2 negatively regulates RON receptor tyrosine kinase and mediates transformation of epithelial cells by jaagsiekte sheep retrovirus

8 July 2018

1 reference

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Senescence, apoptosis and therapy--cutting the lifelines of cancer.

8 July 2018

1 reference

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Role of virus receptor Hyal2 in oncogenic transformation of rodent fibroblasts by sheep betaretrovirus env proteins

8 July 2018

1 reference

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Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase. Recepteur d'origine nantais

8 July 2018

1 reference

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Epithelial-mesenchymal transitions in tumour progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

8 July 2018

1 reference

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Constitutive activation of the RON gene promotes invasive growth but not transformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Identification of the ron gene product as the receptor for the human macrophage stimulating protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296733

Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17588532

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBRC.2007.06.033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17588532%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17588532%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

17588532

1 reference