Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires (Q34978613)

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English	Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires	scientific article

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5 August 2017

Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires (English)

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Europe PubMed Central

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5 August 2017

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Magnus Ø. Arntzen

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11 June 2020

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11 June 2020

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11 June 2020

Gustavo Antônio de Souza

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11 June 2020

Ludvig M Sollid

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Ludvig M Sollid

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11 June 2020

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Elin Bergseng

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11 June 2020

Siri Dørum

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11 June 2020

Ståle Nygård

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12 December 2014

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5 August 2017

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11 June 2020

67

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11 June 2020

2

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11 June 2020

73-84

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11 June 2020

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12 December 2014

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22 June 2022

https://europepmc.org/article/PMC/4297300

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https://scigraph.springernature.com/pub.10.1007/s00251-014-0819-9

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HLA-DQ molecules as affinity matrix for identification of gluten T cell epitopes

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8 July 2018

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.

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8 July 2018

T-cell response to gluten in patients with HLA-DQ2.2 reveals requirement of peptide-MHC stability in celiac disease.

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8 July 2018

Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation

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Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

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Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule

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Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2.

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8 July 2018

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

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8 July 2018

Celiac disease genetics: current concepts and practical applications

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8 July 2018

Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation

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8 July 2018

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.

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8 July 2018

Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

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A global test for groups of genes: testing association with a clinical outcome

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The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

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HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease

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8 July 2018

Analysis of MHC class II antigen processing by quantitation of peptides that constitute nested sets

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Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2).

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Both alpha and beta chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with beta chain residues being most influential

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8 July 2018

The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule

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8 July 2018

Peptide binding characteristics of the coeliac disease-associated DQ(alpha1*0501, beta1*0201) molecule

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8 July 2018

Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients

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Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules

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HLA-DC antigens can serve as recognition elements for human cytotoxic T lymphocytes

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Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer

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Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally processed peptides from HLA-DQ7 (alpha1*0501-beta1*0301): influence of both alpha and beta chain polymorphism in the HLA-DQ peptide binding specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25502872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

1 reference

https://pubmed.ncbi.nlm.nih.gov/25502872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a putative motif for binding of peptides to HLA-DQ2

1 reference

https://pubmed.ncbi.nlm.nih.gov/25502872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S00251-014-0819-9

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11 June 2020

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Europe PubMed Central

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11 June 2020

PubMed publication ID

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Europe PubMed Central

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11 June 2020

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