Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds (Q34979506)

5 August 2017

title

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds (English)

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5 August 2017

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7

Jordan C Tsai

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5 August 2017

Jesse G Zalatan

1

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Lei S Qi

object named as

Lei S Qi

10

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Jonathan Weissman

8

object named as

Jonathan S Weissman

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5 August 2017

Michael E Lee

2

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5 August 2017

Ricardo Almeida

3

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5 August 2017

Luke A Gilbert

4

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5 August 2017

Evan H Whitehead

5

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5 August 2017

Marie La Russa

6

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5 August 2017

John E Dueber

9

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5 August 2017

Wendell A Lim

11

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5 August 2017

language of work or name

English

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publication date

18 December 2014

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5 August 2017

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5 August 2017

volume

160

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5 August 2017

issue

1-2

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5 August 2017

page(s)

339-350

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

5 August 2017

cites work

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Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression

8 July 2018

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Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation

8 July 2018

1 reference

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Employing a combinatorial expression approach to characterize xylose utilization in Saccharomyces cerevisiae

8 July 2018

1 reference

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CRISPR-Cas systems for editing, regulating and targeting genomes

8 July 2018

1 reference

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

8 July 2018

1 reference

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

8 July 2018

1 reference

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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

8 July 2018

1 reference

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Cas9 as a versatile tool for engineering biology

8 July 2018

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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

8 July 2018

1 reference

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Deterministic direct reprogramming of somatic cells to pluripotency

8 July 2018

1 reference

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Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay

8 July 2018

1 reference

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

8 July 2018

1 reference

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

8 July 2018

1 reference

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

8 July 2018

1 reference

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High-level semi-synthetic production of the potent antimalarial artemisinin

8 July 2018

1 reference

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Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

8 July 2018

1 reference

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

8 July 2018

1 reference

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

8 July 2018

1 reference

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Customized optimization of metabolic pathways by combinatorial transcriptional engineering

8 July 2018

1 reference

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Genome regulation by long noncoding RNAs.

8 July 2018

1 reference

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Synthetic biology and the development of tools for metabolic engineering

8 July 2018

1 reference

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Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core

8 July 2018

1 reference

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Organization of intracellular reactions with rationally designed RNA assemblies

8 July 2018

1 reference

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Scaffold proteins: hubs for controlling the flow of cellular information

8 July 2018

1 reference

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RNA templating the epigenome: long noncoding RNAs as molecular scaffolds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

Structural basis for the coevolution of a viral RNA–protein complex

8 July 2018

1 reference

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The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels

8 July 2018

1 reference

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Production of the antimalarial drug precursor artemisinic acid in engineered yeast

8 July 2018

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A new algorithm for RNA secondary structure design

8 July 2018

1 reference

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Translational repression and specific RNA binding by the coat protein of the Pseudomonas phage PP7.

8 July 2018

1 reference

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Unusual transcriptional and translational regulation of the bacteriophage Mu mom operon

8 July 2018

1 reference

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The limits of specificity: an experimental analysis with RNA aptamers to MS2 coat protein variants

8 July 2018

1 reference

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Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

8 July 2018

1 reference

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Krüppel-associated boxes are potent transcriptional repression domains

8 July 2018

1 reference

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Mutations that increase the affinity of a translational repressor for RNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

An RNA mutation that increases the affinity of an RNA-protein interaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

Translational stimulation: RNA sequence and structure requirements for binding of Com protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

What is a Master Regulator?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

Directed evolution of a highly efficient cellobiose utilizing pathway in an industrial Saccharomyces cerevisiae strain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

NUPACK: Analysis and design of nucleic acid systems

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

Engineering yeast transcription machinery for improved ethanol tolerance and production.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297522

10.1016/J.CELL.2014.11.052

26 October 2018

Identifiers

DOI

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5 August 2017

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5 August 2017

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