Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes (Q34979759)

5 August 2017

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title

Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes (English)

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5 August 2017

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4

Martine Raes

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Carine Michiels

series ordinal

1

object named as

Carine Michiels

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Denis Mottet

series ordinal

3

object named as

Denis Mottet

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5 August 2017

Emmanuel Minet

2

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PubMed ID

12398931

5 August 2017

language of work or name

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1 November 2002

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Free Radical Biology and Medicine

5 August 2017

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5 August 2017

33

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5 August 2017

1231-1242

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5 August 2017

9

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Oxygen regulation of gene expression: a study in opposites

5 August 2017

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reactive oxygen species, cell signaling, and cell injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reactive oxygen species as intracellular messengers during cell growth and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

UV activates growth factor receptors via reactive oxygen intermediates

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Enhancement of T cell receptor signaling by a mild oxidative shift in the intracellular thiol pool

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review)

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Redox regulation of fos and jun DNA-binding activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Physical and functional sensitivity of zinc finger transcription factors to redox change

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Role of cysteine residues in regulation of p53 function

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Multiple signals converging on NF-kappaB.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Missing pieces in the NF-kappaB puzzle

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

The IKK complex: an integrator of all signals that activate NF-kappaB?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Role for NF-kappa B in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Stimulation of glutathione peroxidase activity decreases HIV type 1 activation after oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Effects of antioxidant enzyme modulations on interleukin-1-induced nuclear factor kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Interleukin-1 beta induces nuclear factor kappa B in epithelial cells independently of the production of reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Cell type-specific role for reactive oxygen species in nuclear factor-kappaB activation by interleukin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Oxidative stress interference with the nuclear factor-kappa B activation pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitrosation and oxidation in the regulation of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Hydrogen peroxide has opposing effects on IKK activity and IkappaBalpha breakdown in airway epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitric oxide-stimulated guanine nucleotide exchange on p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitric oxide inhibits inflammatory cytokine production by human alveolar macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Exogenous nitric oxide inhibits VCAM-1 expression in human peritoneal mesothelial cells. Role of cyclic GMP and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitric oxide blocks nuclear factor-kappaB activation in alveolar macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Inhibitory action of nitric oxide on circulating tumor necrosis factor-induced NF-kappaB activity and COX-2 transcription in the endothelium of the brain capillaries.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Nitric oxide prevents inducible cyclooxygenase expression by inhibiting nuclear factor-kappa B and nuclear factor-interleukin-6 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Purification and characterization of hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Insights into the role of the von Hippel-Lindau gene product. A key player in hypoxic regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Expression of hypoxia-inducible factor 1: mechanisms and consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Oxygen sensing and molecular adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Cellular mechanism of oxygen sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

NADPH oxidase: a universal oxygen sensor?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Oxygen sensing and signaling: impact on the regulation of physiologically important genes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Role of hydrogen peroxide in hypoxia-induced erythropoietin production

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Modulation of hydrogen peroxide release from vascular endothelial cells by oxygen

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Mechanisms and meaning of cellular oxygen sensing in the organism

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Photometric characteristics of haem proteins in erythropoietin-producing hepatoma cells (HepG2).

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Differential inhibition by iodonium compounds of induced erythropoietin expression

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Cellular respiration during hypoxia. Role of cytochrome oxidase as the oxygen sensor in hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Accumulation of HIF-1alpha under the influence of nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Adaptive responses of the endothelium to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Pathophysiology of ischaemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Oxidant stress and endothelial cell dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

Treating myocardial ischemia-reperfusion injury by targeting endothelial cell transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2901045-6

7 January 2021

10.1016/S0891-5849(02)01045-6

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12398931