Large-scale recombinant adeno-associated virus production (Q34982857)

5 August 2017

1 reference

title

Large-scale recombinant adeno-associated virus production (English)

1 reference

5 August 2017

Robert M Kotin

1

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5 August 2017

publication date

29 April 2011

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5 August 2017

published in

Human Molecular Genetics

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5 August 2017

volume

20

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5 August 2017

issue

R1

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5 August 2017

page(s)

R2-6

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Producing recombinant adeno-associated virus in foster cells: overcoming production limitations using a baculovirus-insect cell expression strategy

5 August 2017

cites work

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A simplified baculovirus-AAV expression vector system coupled with one-step affinity purification yields high-titer rAAV stocks from insect cells

8 July 2018

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Transient transfection methods for clinical adeno-associated viral vector production

8 July 2018

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Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors

8 July 2018

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The titerless infected-cells preservation and scale-up (TIPS) method for large-scale production of NO-sensitive human soluble guanylate cyclase (sGC) from insect cells infected with recombinant baculovirus

8 July 2018

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Manufacturing and characterizing AAV-based vectors for use in clinical studies

8 July 2018

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Immune responses to AAV in clinical trials

8 July 2018

1 reference

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Critical assessment of current adeno-associated viral vector production and quantification methods

8 July 2018

1 reference

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Improvement in the suspension-culture production of recombinant adeno-associated virus-LacZ in HEK-293 cells using polyethyleneimine-DNA complexes in combination with hypothermic treatment

8 July 2018

1 reference

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Economized large-scale production of high yield of rAAV for gene therapy applications exploiting baculovirus expression system

8 July 2018

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High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells

8 July 2018

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Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells

8 July 2018

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Optimization of transfection mediated by calcium phosphate for plasmid rAAV-LacZ (recombinant adeno-associated virus-beta-galactosidase reporter gene) production in suspension-cultured HEK-293 (human embryonic kidney 293) cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Scalable production of adeno-associated virus type 2 vectors via suspension transfection

8 July 2018

1 reference

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Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system

8 July 2018

1 reference

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A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and -5.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Insect cells as a factory to produce adeno-associated virus type 2 vectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

The structure of a replication initiator unites diverse aspects of nucleic acid metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Scaleable chromatographic purification process for recombinant adeno-associated virus (rAAV).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Adeno-associated virus RNAs appear in a temporal order and their splicing is stimulated during coinfection with adenovirus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

An adeno-associated virus (AAV) initiator protein, Rep78, catalyzes the cleavage and ligation of single-stranded AAV ori DNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

High-titer adeno-associated viral vectors from a Rep/Cap cell line and hybrid shuttle virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Adeno-associated virus vectors can be efficiently produced without helper virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Role of the adenovirus DNA-binding protein in in vitro adeno-associated virus DNA replication.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Adenovirus E1A proteins interact with the cellular YY1 transcription factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Rescue and replication signals of the adeno-associated virus 2 genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Replication of the adeno-associated virus DNA termini in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Gene expression in adeno-associated virus vectors: the effects of chimeric mRNA structure, helper virus, and adenovirus VA1 RNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Evidence for covalent attachment of the adeno-associated virus (AAV) rep protein to the ends of the AAV genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

The adenovirus DNA-binding protein stimulates the rate of transcription directed by adenovirus and adeno-associated virus promoters

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

In vitro resolution of covalently joined AAV chromosome ends

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

In vitro rescue of an integrated hybrid adeno-associated virus/simian virus 40 genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Adenovirus containing a deletion of the early region 2A gene allows growth of adeno-associated virus with decreased efficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Rolling hairpin model for replication of parvovirus and linear chromosomal DNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Dystrophin immunity in Duchenne's muscular dystrophy.

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

Novel tools for production and purification of recombinant adenoassociated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

A new strategy for large-scale preparation of high-titer recombinant adeno-associated virus vectors by using packaging cell lines and sulfonated cellulose column chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

Purification of recombinant adeno-associated virus type 8 vectors by ion exchange chromatography generates clinical grade vector stock

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

Chromatography-based purification of adeno-associated virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR141

Scaling-up production of recombinant AAV vectors for clinical applications.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

Cation-exchange high-performance liquid chromatography of recombinant adeno-associated virus type 2.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095058

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21531790

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDR141

1 reference

5 August 2017

1 reference

5 August 2017

1 reference