Recombinant adeno-associated virus vector design and gene expression in the mammalian brain (Q34987182)

5 August 2017

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title

Recombinant adeno-associated virus vector design and gene expression in the mammalian brain (English)

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5 August 2017

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1

Jean-Charles Paterna

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5 August 2017

Hansruedi Büeler

2

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5 August 2017

publication date

1 October 2002

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5 August 2017

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5 August 2017

volume

28

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5 August 2017

issue

2

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5 August 2017

page(s)

208-218

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Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

5 August 2017

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7 January 2021

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

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7 January 2021

Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer

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7 January 2021

Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes

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7 January 2021

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

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7 January 2021

Neurological correction of lysosomal storage in a mucopolysaccharidosis IIIB mouse model by adeno-associated virus-mediated gene delivery

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7 January 2021

Neonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease.

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7 January 2021

Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse

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7 January 2021

Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2.

1 reference

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7 January 2021

Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

1 reference

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7 January 2021

Transduction by adeno-associated virus vectors in the rabbit airway: efficiency, persistence, and readministration.

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7 January 2021

Adeno-associated virus vectors can be efficiently produced without helper virus

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7 January 2021

Factors influencing recombinant adeno-associated virus production

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7 January 2021

Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain

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7 January 2021

Novel tools for production and purification of recombinant adenoassociated virus vectors

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7 January 2021

A helper virus-free packaging system for recombinant adeno-associated virus vectors

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7 January 2021

High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids

1 reference

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7 January 2021

Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Combined injection of rAAV with mannitol enhances gene expression in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant adeno-associated virus serotypes 2- and 5-mediated gene transfer in the mammalian brain: quantitative analysis of heparin co-infusion

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Targeted retrograde gene delivery for neuronal protection

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Remote delivery of rAAV-GFP to the rat brainstem through the recurrent laryngeal nerve.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Selective and rapid uptake of adeno-associated virus type 2 in brain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Integrin alphaVbeta5 is not involved in adeno-associated virus type 2 (AAV2) infection

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

The interaction of heparin sulfate and adeno-associated virus 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Infection of purified nuclei by adeno-associated virus 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Endocytosis of adeno-associated virus type 5 leads to accumulation of virus particles in the Golgi compartment

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant adeno-associated virus for muscle directed gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Gene transfer into the CNS using recombinant adeno-associated virus: analysis of vector DNA forms resulting in sustained expression

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Inactivation of the very strong HCMV immediate early promoter by DNA CpG methylation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Unusual cell specific expression of a major human cytomegalovirus immediate early gene promoter-lacZ hybrid gene in transgenic mouse embryos

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

The cytomegalovirus enhancer: a pan-active control element in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Selective neuronal expression of green fluorescent protein with cytomegalovirus promoter reveals entire neuronal arbor in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Chronic ethanol increases adeno-associated viral transgene expression in rat liver via oxidant and NFkappaB-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Usefulness of double gene construct for rapid identification of transgenic mice exhibiting tissue-specific gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

A minimal human MBP promoter-lacZ transgene is appropriately regulated in developing brain and after optic enucleation, but not in shiverer mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virus

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Measurement of neuron-specific (NSE) and non-neuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Neuron-specific enolase reflects metabolic activity in mesencephalic neurons of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Generation of aberrant sprouting in the adult rat brain by GAP-43 somatic gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

1 reference

7 January 2021

Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Widespread gene delivery and structure-specific patterns of expression in the brain after intraventricular injections of neonatal mice with an adeno-associated virus vector

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Long-term restoration of striatal L-aromatic amino acid decarboxylase activity using recombinant adeno-associated viral vector gene transfer in a rodent model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

'Green mice' as a source of ubiquitous green cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Inducible long-term gene expression in brain with adeno-associated virus gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

A generic intron increases gene expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

CRM1-dependent function of a cis-acting RNA export element

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Optimization of transcriptional regulatory elements for constructing plasmid vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Internal ribosome entry site biology and its use in expression vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

A novel dicistronic AAV vector using a short IRES segment derived from hepatitis C virus genome

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Comparison of picornaviral IRES-driven internal initiation of translation in cultured cells of different origins.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

Proteolytic processing of picornaviral polyprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900225-6

7 January 2021

10.1016/S1046-2023(02)00225-6

Identifiers

DOI

1 reference

5 August 2017

1 reference