Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain (Q34987192)

5 August 2017

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title

Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain (English)

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5 August 2017

Helen L Fitzsimons

1

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PubMed ID

12413421

5 August 2017

Ross J Bland

series ordinal

2

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PubMed ID

12413421

5 August 2017

Matthew J During

series ordinal

3

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5 August 2017

1 October 2002

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5 August 2017

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5 August 2017

28

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5 August 2017

2

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5 August 2017

227-236

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The cytomegalovirus enhancer: a pan-active control element in transgenic mice

5 August 2017

1 reference

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7 January 2021

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

1 reference

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7 January 2021

Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity

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7 January 2021

Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS

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7 January 2021

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector

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7 January 2021

Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression

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7 January 2021

Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors.

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7 January 2021

Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.

1 reference

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7 January 2021

Elimination of lysosomal storage in brains of MPS VII mice treated by intrathecal administration of an adeno-associated virus vector

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7 January 2021

Tropism of AAV-2 vectors for neurons of the globus pallidus

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7 January 2021

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

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7 January 2021

Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats

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7 January 2021

Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease

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7 January 2021

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

1 reference

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7 January 2021

Long-term restoration of striatal L-aromatic amino acid decarboxylase activity using recombinant adeno-associated viral vector gene transfer in a rodent model of Parkinson's disease

1 reference

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7 January 2021

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

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7 January 2021

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

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7 January 2021

Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats.

1 reference

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7 January 2021

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease

1 reference

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7 January 2021

Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction

1 reference

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7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

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7 January 2021

CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged beta-glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Adeno-associated virus vectors: activity and applications in the CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Prevention of systemic clinical disease in MPS VII mice following AAV-mediated neonatal gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

1 reference

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7 January 2021

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

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7 January 2021

Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1046-2023%2802%2900227-X

7 January 2021

Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

1 reference

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7 January 2021

Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration

1 reference

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7 January 2021

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

1 reference

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7 January 2021

Adeno-associated virus vector-mediated bcl-2 gene transfer into post-ischemic gerbil brain in vivo: prospects for gene therapy of ischemia-induced neuronal death

1 reference

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7 January 2021

Gene transfer by adeno-associated virus vectors into the central nervous system

1 reference

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7 January 2021

In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression.

1 reference

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7 January 2021

Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.

1 reference

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7 January 2021

Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control

1 reference

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7 January 2021

Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

1 reference

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7 January 2021

Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors

1 reference

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7 January 2021

Combined injection of rAAV with mannitol enhances gene expression in the rat brain

1 reference

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7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

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7 January 2021

Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons

1 reference

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7 January 2021

A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons

1 reference

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7 January 2021

GFAP promoter directs astrocyte-specific expression in transgenic mice.

1 reference

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7 January 2021

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

1 reference

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7 January 2021

Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element

1 reference

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7 January 2021

Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression

1 reference

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7 January 2021

Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus

1 reference

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7 January 2021

Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy

1 reference

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7 January 2021

Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain

1 reference

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7 January 2021

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

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7 January 2021

AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection

1 reference

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7 January 2021

Selective and rapid uptake of adeno-associated virus type 2 in brain

1 reference

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7 January 2021

Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: establishment of a glial cell line with a functional CD4 receptor

1 reference

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7 January 2021

A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain

1 reference

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7 January 2021

Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity

1 reference

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7 January 2021

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

1 reference

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7 January 2021

A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation

1 reference

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7 January 2021

Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy

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7 January 2021

Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

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7 January 2021

Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors

1 reference

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7 January 2021

Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison

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7 January 2021

10.1016/S1046-2023(02)00227-X

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12413421