Cytokines: promoters and dampeners of autoimmunity (Q34987307)

5 August 2017

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title

Cytokines: promoters and dampeners of autoimmunity (English)

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5 August 2017

Natasha Hill

1

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5 August 2017

Nora Sarvetnick

series ordinal

2

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5 August 2017

publication date

1 December 2002

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Current Opinion in Immunology

5 August 2017

published in

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5 August 2017

volume

14

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5 August 2017

issue

6

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5 August 2017

page(s)

791-797

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The role of cytokines in autoimmunity

5 August 2017

cites work

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7 January 2021

Regulation of autoimmunity by proinflammatory cytokines

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7 January 2021

Increased entry into the IFN-gamma effector pathway by CD4+ T cells selected by I-Ag7 on a nonobese diabetic versus C57BL/6 genetic background

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7 January 2021

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

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7 January 2021

Mechanism underlying counterregulation of autoimmune diabetes by IL-4.

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7 January 2021

Cellular and molecular mechanisms for the initiation and progression of beta cell destruction resulting from the collaboration between macrophages and T cells

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7 January 2021

IFN-gamma affects homing of diabetogenic T cells

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7 January 2021

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

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7 January 2021

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

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7 January 2021

Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes

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7 January 2021

Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation.

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7 January 2021

Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis

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7 January 2021

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

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7 January 2021

Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis

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7 January 2021

Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease

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7 January 2021

T helper 2 (Th2) T cells induce acute pancreatitis and diabetes in immune-compromised nonobese diabetic (NOD) mice

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7 January 2021

The role of IFN-gamma in the production of Th2 subpopulations: implications for variable Th2-mediated pathologies in autoimmunity

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7 January 2021

T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis

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7 January 2021

IL-4 exacerbates disease in a Th1 cell transfer model of colitis

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7 January 2021

Autoreactivity by design: innate B and T lymphocytes

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7 January 2021

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

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7 January 2021

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

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7 January 2021

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

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7 January 2021

Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

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7 January 2021

Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

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7 January 2021

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

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7 January 2021

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

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7 January 2021

A thymic precursor to the NK T cell lineage

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7 January 2021

The role of IL-4 in regulation of murine collagen-induced arthritis

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7 January 2021

The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy

1 reference

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7 January 2021

Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway

1 reference

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7 January 2021

Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety

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7 January 2021

Regulatory T cells in the control of immune pathology.

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7 January 2021

Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

1 reference

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7 January 2021

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

1 reference

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7 January 2021

Interleukin-10 and the interleukin-10 receptor

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7 January 2021

Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

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7 January 2021

Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys

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7 January 2021

Transforming growth factor-beta in T-cell biology

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7 January 2021

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

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7 January 2021

TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression

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7 January 2021

Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion

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7 January 2021

TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype

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7 January 2021

Role of TGFbeta in development of spontaneous autoimmune thyroiditis in NOD.H-2h4 mice

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7 January 2021

IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18

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7 January 2021

The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes

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7 January 2021

Suppression of T(h)1 cell activation and prevention of autoimmune diabetes in NOD mice by local expression of viral IL-10

1 reference

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7 January 2021

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Constitutive beta cell expression of IL-12 does not perturb self-tolerance but intensifies established autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

1 reference

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7 January 2021

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

A Proinflammatory Role of IL-18 in the Development of Spontaneous Autoimmune Disease

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7 January 2021

Interleukin-18 regulates both Th1 and Th2 responses

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7 January 2021

Type 1 IFNs and regulation of TH1 responses: enigmas both resolved and emerge

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7 January 2021

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

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7 January 2021

Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus

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7 January 2021

Target cell defense prevents the development of diabetes after viral infection.

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7 January 2021

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

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7 January 2021

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

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7 January 2021

Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure

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7 January 2021

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

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7 January 2021

Innate response cytokines in inflammatory synovitis: a role for interleukin-15.

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7 January 2021

A role for IL-15 in driving the onset of spontaneous autoimmune thyroiditis?

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7 January 2021

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

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7 January 2021

IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity

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7 January 2021

Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

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7 January 2021

The natural killer cell -- friend or foe in autoimmune disease?

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7 January 2021

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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7 January 2021

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

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7 January 2021

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

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7 January 2021

Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900403-X

7 January 2021

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

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7 January 2021

Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice

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7 January 2021

IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis

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7 January 2021

Prevention of murine experimental autoimmune orchitis by recombinant human interleukin-6

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7 January 2021

Curative effects of recombinant human Interleukin-6 in DA rats with protracted relapsing experimental allergic encephalomyelitis

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7 January 2021

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

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7 January 2021

10.1016/S0952-7915(02)00403-X

Identifiers

DOI

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release_5mhv6ttaazeobkzugyjkhcw6ki

5 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/5mhv6ttaazeobkzugyjkhcw6ki

24 November 2022

mapped directly with Wikidata item

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