IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H) (Q34988311)

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English	IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H) (English)

1 reference

Europe PubMed Central

5 August 2017

multiple sclerosis

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Alastair Compston

9

object named as

Alastair Compston

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Europe PubMed Central

5 August 2017

author name string

Joanne L Jones

1

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Europe PubMed Central

5 August 2017

Chia-Ling Phuah

2

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Europe PubMed Central

5 August 2017

Amanda L Cox

3

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Europe PubMed Central

5 August 2017

Sara A Thompson

4

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Europe PubMed Central

5 August 2017

Maria Ban

5

1 reference

Europe PubMed Central

5 August 2017

Jacqueline Shawcross

6

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Europe PubMed Central

5 August 2017

Amie Walton

7

1 reference

Europe PubMed Central

5 August 2017

Stephen J Sawcer

8

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Europe PubMed Central

5 August 2017

Alasdair J Coles

10

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Europe PubMed Central

5 August 2017

language of work or name

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publication date

22 June 2009

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Europe PubMed Central

5 August 2017

Journal of Clinical Investigation

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Europe PubMed Central

5 August 2017

119

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Europe PubMed Central

5 August 2017

7

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Europe PubMed Central

5 August 2017

2052-2061

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Europe PubMed Central

5 August 2017

Alemtuzumab vs. interferon beta-1a in early multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Autoimmunity following haematopoietic stem-cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

A second major histocompatibility complex susceptibility locus for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Autoimmunity during lymphopenia: a two-hit model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Competition for self-peptide-MHC complexes and cytokines between naive and memory CD8+ T cells expressing the same or different T cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Homeostatic proliferation is a barrier to transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

HIV and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Sequential occurrence of thyroid autoantibodies and Graves' disease after immune restoration in severely immunocompromised human immunodeficiency virus-1-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Flow cytometric analysis of cell division history using dilution of carboxyfluorescein diacetate succinimidyl ester, a stably integrated fluorescent probe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Impaired apoptotic deletion of myelin basic protein-reactive T cells in patients with multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Acquired autoimmune thrombocytopenia post-bone marrow transplantation for severe combined immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

8 July 2018

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Refining genetic associations in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

IL-21 modulates CD4+ CD25+ regulatory T-cell homeostasis in experimental autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Defective lymphocyte caspase-3 expression in type 1 diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Characteristics of autoimmune thyroid disease occurring as a late complication of immune reconstitution in patients with advanced human immunodeficiency virus (HIV) disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Cutting edge: naive T cells masquerading as memory cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2701868

26 October 2018

Impaired caspase-3 expression by peripheral T cells in chronic autoimmune thyroiditis and in autoimmune polyendocrine syndrome-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective T cell Fas function in patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Campath-1H antibody on human hematopoietic progenitors in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired apoptosis in mitogen-stimulated lymphocytes of patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network

1 reference

https://pubmed.ncbi.nlm.nih.gov/19546505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1172/JCI37878

1 reference

Europe PubMed Central

5 August 2017

release_bgnftap6frctzdpn5a5noebbja

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https://api.fatcat.wiki/v0/release/bgnftap6frctzdpn5a5noebbja

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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