Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities (Q34996991)

5 August 2017

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title

Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities (English)

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5 August 2017

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1

Derek LeRoith

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PubMed ID

12431757

5 August 2017

language of work or name

English

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publication date

1 October 2002

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American Journal of Medicine

5 August 2017

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5 August 2017

113 Suppl 6A

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5 August 2017

3S-11S

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Tactics for type II diabetes

5 August 2017

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https://api.crossref.org/works/10.1016%2FS0002-9343%2802%2901276-7

Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2802%2901276-7

Fatty acids and insulin resistance

7 January 2021

1 reference

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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

7 January 2021

1 reference

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The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

7 January 2021

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

7 January 2021

1 reference

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

7 January 2021

1 reference

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

7 January 2021

1 reference

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Assessing the potential for alpha-glucosidase inhibitors in prediabetic states.

7 January 2021

1 reference

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

7 January 2021

1 reference

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Effect of troglitazone on insulin sensitivity and pancreatic beta-cell function in women at high risk for NIDDM.

7 January 2021

1 reference

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Banting lecture 1990. Beta-cells in type II diabetes mellitus

7 January 2021

1 reference

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Triggering and amplifying pathways of regulation of insulin secretion by glucose

7 January 2021

1 reference

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Of mice and men: K(ATP) channels and insulin secretion

7 January 2021

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7 January 2021

Evening insulin strategy

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Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

7 January 2021

1 reference

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Intracellular organization of insulin signaling and GLUT4 translocation

7 January 2021

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Troglitazone not only increases GLUT4 but also induces its translocation in rat adipocytes

7 January 2021

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Hexosamines as mediators of nutrient sensing and regulation in diabetes.

7 January 2021

1 reference

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Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

7 January 2021

1 reference

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Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

7 January 2021

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Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment.

7 January 2021

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The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.

7 January 2021

1 reference

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The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus

7 January 2021

1 reference

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Free fatty acids-the link between obesity and insulin resistance

7 January 2021

1 reference

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Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

7 January 2021

1 reference

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Skeletal muscle triglyceride levels are inversely related to insulin action.

7 January 2021

1 reference

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Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance

7 January 2021

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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

7 January 2021

1 reference

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Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men.

7 January 2021

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The hormone resistin links obesity to diabetes

7 January 2021

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

7 January 2021

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The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

7 January 2021

1 reference

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Effect of angiotensin peptides on PAI-1 expression and production in human adipocytes.

7 January 2021

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Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis

7 January 2021

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7 January 2021

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Identifiers

DOI

10.1016/S0002-9343(02)01276-7

1 reference

5 August 2017

1 reference

PubMed ID

12431757