Lost in translation: an assessment and perspective for computational microRNA target identification (Q35005629)

5 August 2017

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title

Lost in translation: an assessment and perspective for computational microRNA target identification (English)

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5 August 2017

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Manolis Maragkakis

2

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Panagiotis Alexiou

object named as

Panagiotis Alexiou

1

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Martin Reczko

object named as

Martin Reczko

4

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author name string

Giorgos L Papadopoulos

3

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PubMed ID

19789267

5 August 2017

Artemis G Hatzigeorgiou

5

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PubMed ID

19789267

5 August 2017

language of work or name

English

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publication date

29 September 2009

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5 August 2017

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5 August 2017

25

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5 August 2017

3049-3055

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5 August 2017

23

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The small RNA profile during Drosophila melanogaster development

5 August 2017

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MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

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The impact of microRNAs on protein output

21 January 2018

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MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines

21 January 2018

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MicroRNAs: genomics, biogenesis, mechanism, and function

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Identification of human microRNA targets from isolated argonaute protein complexes

21 January 2018

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MicroRNA signatures in human cancers

21 January 2018

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MicroRNAs modulate hematopoietic lineage differentiation

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miRNAs, cancer, and stem cell division

21 January 2018

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Processing of primary microRNAs by the Microprocessor complex

21 January 2018

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Specificity of microRNA target selection in translational repression

21 January 2018

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Isolation of microRNA targets by miRNP immunopurification

21 January 2018

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Oncomirs - microRNAs with a role in cancer

21 January 2018

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Regulatory mechanisms of microRNAs involvement in cancer

21 January 2018

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Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

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Inference of miRNA targets using evolutionary conservation and pathway analysis

21 January 2018

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miRNAs: Little known mediators of oncogenesis

21 January 2018

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MicroRNA expression and function in cancer

21 January 2018

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miRBase: tools for microRNA genomics

21 January 2018

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

21 January 2018

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mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts

21 January 2018

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The role of microRNA genes in papillary thyroid carcinoma

21 January 2018

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A microRNA polycistron as a potential human oncogene

21 January 2018

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

21 January 2018

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The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

21 January 2018

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MicroRNA gene expression deregulation in human breast cancer

21 January 2018

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Combinatorial microRNAs: working together to make a difference

21 January 2018

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MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression

21 January 2018

1 reference

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21 January 2018

Human MicroRNA targets

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The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

1 reference

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The role of site accessibility in microRNA target recognition

21 January 2018

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The developmental role of microRNA in plants

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

A combined computational-experimental approach predicts human microRNA targets

21 January 2018

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Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

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Identification of novel genes coding for small expressed RNAs

21 January 2018

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Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia

21 January 2018

1 reference

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

21 January 2018

1 reference

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Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

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An extensive class of small RNAs in Caenorhabditis elegans

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Potent effect of target structure on microRNA function.

21 January 2018

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Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

21 January 2018

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Accurate microRNA target prediction correlates with protein repression levels

21 January 2018

1 reference

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A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

21 January 2018

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The database of experimentally supported targets: a functional update of TarBase

21 January 2018

1 reference

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Widespread changes in protein synthesis induced by microRNAs

21 January 2018

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miR-21-mediated tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

MicroRNAs as a potential magic bullet in cancer.

21 January 2018

1 reference

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Synergistic action of the microRNA-17 polycistron and Myc in aggressive cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Endogenous human microRNAs that suppress breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

21 January 2018

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MicroRNA expression in zebrafish embryonic development

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

21 January 2018

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https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

MicroRNAs: role in cardiovascular biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIOINFORMATICS%2FBTP565

10.1093/BIOINFORMATICS/BTP565

21 January 2018

Identifiers

DOI

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journals/bioinformatics/AlexiouMPRH09

5 August 2017

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DBLP Dataset 2021-01-02

28 January 2021

1 reference

PubMed ID

19789267