Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK (Q35005708)

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English	Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK (English)

1 reference

Europe PubMed Central

5 August 2017

lipopolysaccharide

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object named as

Annette Ives

3

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author name string

Johji Nomura

1

1 reference

Europe PubMed Central

5 August 2017

Nathalie Busso

2

1 reference

Europe PubMed Central

5 August 2017

Syunsuke Tsujimoto

4

1 reference

Europe PubMed Central

5 August 2017

Mizuho Tamura

5

1 reference

Europe PubMed Central

5 August 2017

Alexander So

6

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Europe PubMed Central

5 August 2017

Yoshihiro Yamanaka

7

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Europe PubMed Central

5 August 2017

language of work or name

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publication date

25 September 2013

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Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

8

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Europe PubMed Central

5 August 2017

e75527

1 reference

Europe PubMed Central

5 August 2017

9

1 reference

Europe PubMed Central

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

25 September 2013

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April 2022 Public Data File from Crossref

copyright status

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Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress

1 reference

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The role of peroxidases in the pathogenesis of atherosclerosis

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Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production

1 reference

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Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome

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MAP kinase phosphatase-1, a critical negative regulator of the innate immune response

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The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase

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Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress

1 reference

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Free radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin

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Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications.

1 reference

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Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages

1 reference

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Antioxidant responses to oxidant-mediated lung diseases

1 reference

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Upregulation of xanthine oxidase by lipopolysaccharide, interleukin-1, and hypoxia. Role in acute lung injury.

1 reference

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Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia

1 reference

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Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.

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Allopurinol attenuates left ventricular remodeling and dysfunction after experimental myocardial infarction: a new action for an old drug?

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Mononuclear Phagocyte Xanthine Oxidoreductase Contributes to Cytokine-Induced Acute Lung Injury

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Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.

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Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers

1 reference

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Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy

1 reference

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Role of Increased Production of Superoxide Anions by NAD(P)H Oxidase and Xanthine Oxidase in Prolonged Endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24086554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development

1 reference

https://pubmed.ncbi.nlm.nih.gov/24086554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypouricemic effect of the novel xanthine oxidase inhibitor, TEI-6720, in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/24086554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0075527

1 reference

Europe PubMed Central

5 August 2017

2013PLoSO...875527N

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1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

ResearchGate publication ID

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