Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. (Q35012498)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16945901%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials (English)

1 reference

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amyotrophic lateral sclerosis

29 December 2019

main subject

1 reference

1 reference

1

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29 December 2019

Mauro Cozzolino

2

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29 December 2019

Maria Teresa Carrì

9

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29 December 2019

author name string

Claudia Crosio

3

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29 December 2019

Monica Nencini

4

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29 December 2019

Arianna Casciati

5

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29 December 2019

Edith Butler Gralla

6

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29 December 2019

Giuseppe Rotilio

7

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29 December 2019

Joan Selverstone Valentine

8

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29 December 2019

language of work or name

English

0 references

publication date

30 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16945901%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

29 December 2019

published in

1 reference

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29 December 2019

volume

103

1 reference

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29 December 2019

issue

37

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29 December 2019

page(s)

13860-13865

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Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

29 December 2019

cites work

1 reference

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Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation

8 July 2018

1 reference

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Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis.

8 July 2018

1 reference

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Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

8 July 2018

1 reference

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Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis

8 July 2018

1 reference

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Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.

8 July 2018

1 reference

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Different immunoreactivity against monoclonal antibodies between wild-type and mutant copper/zinc superoxide dismutase linked to amyotrophic lateral sclerosis

8 July 2018

1 reference

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Mitochondrial degeneration in amyotrophic lateral sclerosis.

8 July 2018

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Lessons from models of SOD1-linked familial ALS.

8 July 2018

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Oxidative stress in neurodegeneration: cause or consequence?

8 July 2018

1 reference

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Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

8 July 2018

1 reference

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Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

8 July 2018

1 reference

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Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.

8 July 2018

1 reference

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Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

8 July 2018

1 reference

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Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

8 July 2018

1 reference

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Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction

8 July 2018

1 reference

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Do oxidatively modified proteins cause ALS?

8 July 2018

1 reference

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Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

8 July 2018

1 reference

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Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis.

8 July 2018

1 reference

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Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

8 July 2018

1 reference

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

8 July 2018

1 reference

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Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection.

8 July 2018

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Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

8 July 2018

1 reference

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Increase of Cu,Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein

8 July 2018

1 reference

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Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

8 July 2018

1 reference

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Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

8 July 2018

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Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.

21 January 2018

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Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature

21 January 2018

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Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

21 January 2018

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Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

21 January 2018

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Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

21 January 2018

1 reference

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Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.

21 January 2018

1 reference

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Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

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Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant. Insights into the molecular basis for dimer stability

21 January 2018

1 reference

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N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

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Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16945901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16945901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16945901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0605814103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16945901%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16945901%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference