Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH. (Q35014238)

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English	Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH. (English)

1 reference

Europe PubMed Central

5 August 2017

Geoffrey Farrell

7

object named as

Geoffrey C Farrell

1 reference

Europe PubMed Central

5 August 2017

6

object named as

Narci C Teoh

1 reference

Europe PubMed Central

5 August 2017

author name string

George N Ioannou

1

1 reference

Europe PubMed Central

5 August 2017

Derrick M Van Rooyen

2

1 reference

Europe PubMed Central

5 August 2017

Christopher Savard

3

1 reference

Europe PubMed Central

5 August 2017

W Geoffrey Haigh

4

1 reference

Europe PubMed Central

5 August 2017

Matthew M Yeh

5

1 reference

Europe PubMed Central

5 August 2017

publication date

17 December 2014

1 reference

Europe PubMed Central

5 August 2017

Journal of Lipid Research

1 reference

Europe PubMed Central

5 August 2017

56

1 reference

Europe PubMed Central

5 August 2017

2

1 reference

Europe PubMed Central

5 August 2017

277-285

1 reference

Europe PubMed Central

5 August 2017

2013 ACC/AHA guideline recommends fixed-dose strategies instead of targeted goals to lower blood cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Steatohepatitis in laboratory opossums exhibiting a high lipemic response to dietary cholesterol and fat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

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LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease

1 reference

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Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

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Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis.

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8 July 2018

Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis

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8 July 2018

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

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Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis

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8 July 2018

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

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8 July 2018

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

NPC1L1 and cholesterol transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

The inflammasomes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Esterified cholesterol is highly localized to Bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid

1 reference

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8 July 2018

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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8 July 2018

The Nalp3 inflammasome is essential for the development of silicosis

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

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8 July 2018

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

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8 July 2018

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

1 reference

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8 July 2018

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4306682

8 July 2018

A lipidomic analysis of nonalcoholic fatty liver disease.

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21 January 2018

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.

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https://api.crossref.org/works/10.1194%2FJLR.M053785

21 January 2018

Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice

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Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

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21 January 2018

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

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https://api.crossref.org/works/10.1194%2FJLR.M053785

21 January 2018

Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population.

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M053785

21 January 2018

Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease.

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M053785

21 January 2018

A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice.

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M053785

21 January 2018

In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.

1 reference

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21 January 2018

Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study.

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21 January 2018

Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial.

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A pilot study using simvastatin in the treatment of nonalcoholic steatohepatitis: A randomized placebo-controlled trial.

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Adipocyte death, adipose tissue remodeling, and obesity complications

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12 December 2020

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10.1194/JLR.M053785

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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