IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition. (Q35014600)

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English	IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition.	scientific article

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30 January 2020

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition (English)

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30 January 2020

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30 January 2020

Sashko Damjanovski

2

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30 January 2020

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Logan A Walsh

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5 August 2017

Sashko Damjanovski

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5 August 2017

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2 May 2011

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30 January 2020

Cell Communication and Signaling

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30 January 2020

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30 January 2020

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30 January 2020

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30 January 2020

https://scigraph.springernature.com/pub.10.1186/1478-811x-9-10

0 references

Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression pattern

1 reference

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8 July 2018

TGFbeta signalling: a complex web in cancer progression

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8 July 2018

Effect of type 1 insulin-like growth factor receptor targeted therapy on chemotherapy in human cancer and the mechanisms involved

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8 July 2018

The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.

1 reference

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8 July 2018

Review of the activation of TGF-beta in immunity

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8 July 2018

Matrix metalloproteinases and the regulation of tissue remodelling

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8 July 2018

Matrix metalloproteinases in development and disease

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8 July 2018

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

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8 July 2018

Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin.

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8 July 2018

Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-alpha and TGF-beta

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8 July 2018

It's the matrix! ECM, proteases, and cancer

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8 July 2018

Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development

1 reference

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8 July 2018

Making sense of latent TGFbeta activation

1 reference

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8 July 2018

Direct evidence for a role of beta-catenin/LEF-1 signaling pathway in induction of EMT.

1 reference

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8 July 2018

The IGF system and breast cancer

1 reference

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8 July 2018

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

1 reference

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8 July 2018

Role of transforming growth factor beta in human disease

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8 July 2018

Endocrine effects of IGF-I on normal and transformed breast epithelial cells: potential relevance to strategies for breast cancer treatment and prevention

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8 July 2018

TGF-beta latency: biological significance and mechanisms of activation

1 reference

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8 July 2018

Regulation of development and differentiation by the extracellular matrix

1 reference

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8 July 2018

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1 reference

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21 January 2018

Circulating levels of sex steroids and prolactin in premenopausal women and risk of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21535875

12 December 2020

based on heuristic

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Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21535875

12 December 2020

based on heuristic

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[Activation of latent TGF-beta. A required mechanism for vascular integrity]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21535875

12 December 2020

based on heuristic

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Keeping order in the neighborhood: new roles for TGFbeta in maintaining epithelial homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21535875

12 December 2020

based on heuristic

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Identifiers

10.1186/1478-811X-9-10

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30 January 2020

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30 January 2020

1 reference

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30 January 2020

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