Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. (Q35015948)

5 August 2017

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title

Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. (English)

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5 August 2017

Natasa Debeljak

1

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5 August 2017

Martina Fink

series ordinal

2

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5 August 2017

Damjana Rozman

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 January 2003

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Archives of Biochemistry and Biophysics

5 August 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

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5 August 2017

volume

409

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5 August 2017

issue

1

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5 August 2017

page(s)

159-171

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Cytochrome P450 and the individuality of species

5 August 2017

cites work

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Sterol 14-demethylase P450 (CYP51) provides a breakthrough for the discussion on the evolution of cytochrome P450 gene superfamily

7 January 2021

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Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: II. Evolutionary analysis of protein and gene structures

7 January 2021

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Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species

7 January 2021

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Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals

7 January 2021

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CYP51-like gene of Mycobacterium tuberculosis actually encodes a P450 similar to eukaryotic CYP51

7 January 2021

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Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis

7 January 2021

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A sterol biosynthetic pathway in Mycobacterium.

7 January 2021

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Chemical structure of sterols that activate oocyte meiosis

7 January 2021

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Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family

7 January 2021

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Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana.

7 January 2021

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The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

7 January 2021

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The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

7 January 2021

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Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes

7 January 2021

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Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: I. Structural analyses of the gene and multiple sizes of mRNA

7 January 2021

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Structure of the pig sterol 14alpha-demethylase (CYP51) gene and its expression in the testis and other tissues

7 January 2021

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Elevated Expression of Lanosterol 14α-Demethylase (CYP51) and the Synthesis of Oocyte Meiosis-Activating Sterols in Postmeiotic Germ Cells of Male Rats1

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A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).

7 January 2021

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Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis

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LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism.

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Specificity in cholesterol regulation of gene expression by coevolution of sterol regulatory DNA element and its binding protein

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Gonadotropin-dependent expression of sterol 14-demethylase P450 (CYP51) in rat ovaries and its contribution to the production of a meiosis-activating steroid

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Insulin is the essential factor maintaining the constitutive expression of hepatic sterol 14-demethylase P450 (CYP51)

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Dual role of signaling pathways leading to Ca(2+) and cyclic AMP elevation in host cell invasion by Trypanosoma cruzi

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CBP-independent activation of CREM and CREB by the LIM-only protein ACT

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Occurrence of a P450 showing high homology to yeast lanosterol 14-demethylase (P450(14DM)) in the rat liver

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Lanosterol 14-demethylase activity expressed in rat brain microsomes

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Sterol 14-demethylase P450 activity expressed in rat gonads: contribution to the formation of mammalian meiosis-activating sterol.

7 January 2021

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The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

7 January 2021

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Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

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Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents.

7 January 2021

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Generation of a complete, soluble, and catalytically active sterol 14 alpha-demethylase-reductase complex.

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Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol

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inferred from DOI database lookup

7 January 2021

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Gonadotropin-induced resumption of oocyte meiosis and meiosis-activating sterols

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https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900418-6

inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1016/S0003-9861(02)00418-6

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5 August 2017

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