Methylation determines fibroblast activation and fibrogenesis in the kidney (Q35019643)

5 August 2017

Methylation determines fibroblast activation and fibrogenesis in the kidney (English)

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5 August 2017

Wibke Bechtel

1

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5 August 2017

Scott McGoohan

2

1 reference

5 August 2017

Elisabeth M Zeisberg

3

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5 August 2017

Gerhard A Müller

4

1 reference

5 August 2017

Hubert Kalbacher

5

1 reference

5 August 2017

David J Salant

6

1 reference

5 August 2017

Claudia A Müller

7

1 reference

5 August 2017

Raghu Kalluri

8

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5 August 2017

Michael Zeisberg

9

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5 August 2017

language of work or name

English

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publication date

25 April 2010

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5 August 2017

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5 August 2017

16

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5 August 2017

544-550

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5 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nm.2135

5 August 2017

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Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers.

8 July 2018

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The myofibroblast: one function, multiple origins

8 July 2018

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The epigenomics of cancer

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Targeting fibrosis in systemic sclerosis

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Renal fibroblasts and myofibroblasts in chronic kidney disease

8 July 2018

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8 July 2018

Fibroblasts in cancer

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The epigenome as a molecular marker and target

8 July 2018

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Signaling interplay in Ras superfamily function

8 July 2018

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A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

8 July 2018

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Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease

8 July 2018

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The renal papilla is a niche for adult kidney stem cells

8 July 2018

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Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations

8 July 2018

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Recent advances in neurofibromatosis type 1.

8 July 2018

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Gene silencing in cancer in association with promoter hypermethylation

8 July 2018

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Targeting RAS signalling pathways in cancer therapy

8 July 2018

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TGF-beta signaling in renal disease

8 July 2018

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Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

8 July 2018

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TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2).

8 July 2018

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Methylation-induced repression--belts, braces, and chromatin

8 July 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

8 July 2018

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RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis

8 July 2018

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Role for DNA methylation in genomic imprinting

8 July 2018

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Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

8 July 2018

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Alterations in DNA methylation in human colon neoplasia

8 July 2018

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8 July 2018

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ras oncogenes in human cancer: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

Mechanisms of tubulointerstitial fibrosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis.

8 July 2018

1 reference

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

8 July 2018

1 reference

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Factors associated with reactive and reparative fibrosis of the myocardium

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

Molecular insights into renal interstitial fibrosis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3106179

Targeting Ras genes in kidney disease

25 October 2018

1 reference

12 December 2020

Characterization of human renal fibroblasts in health and disease: I. Immunophenotyping of cultured tubular epithelial cells and fibroblasts derived from kidneys with histologically proven interstitial fibrosis

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12 December 2020

Targeting TGF-beta for treatment of disease

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12 December 2020

Macrophage and myofibroblast involvement in ischemic acute renal failure is attenuated by endothelin receptor antagonists

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12 December 2020

Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure

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12 December 2020

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

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12 December 2020

DNA methylation: Bisulphite modification and analysis

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12 December 2020

The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid

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7 January 2021

A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles

1 reference

7 January 2021

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

1 reference

7 January 2021

Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition

1 reference

7 January 2021

Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.2135

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference