SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer (Q35021702)

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English	SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

colorectal cancer

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based on heuristic

inferred from title

metastatic colon cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

author name string

Liu Huang

1

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5 August 2017

Tao Zhang

2

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5 August 2017

Conghua Xie

3

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5 August 2017

Xin Liao

4

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5 August 2017

Qianqian Yu

5

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5 August 2017

Jueping Feng

6

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5 August 2017

Hong Ma

7

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5 August 2017

Jing Dai

8

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5 August 2017

Min Li

9

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5 August 2017

Jigui Chen

10

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5 August 2017

Aihua Zang

11

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5 August 2017

Qian Wang

12

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5 August 2017

Shuwang Ge

13

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5 August 2017

Kai Qin

14

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5 August 2017

Juan Cai

15

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5 August 2017

Xianglin Yuan

16

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5 August 2017

language of work or name

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publication date

15 October 2013

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5 August 2017

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5 August 2017

8

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5 August 2017

10

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Europe PubMed Central

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5 August 2017

e77223

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

15 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Impact of the UGT1A1*28 allele on response to irinotecan: a systematic review and meta-analysis

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Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

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Phase 2 study of capecitabine and irinotecan combination chemotherapy (modified XELIRI regimen) in patients with advanced gastric cancer.

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Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer

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Subcellular localization and distribution of the reduced folate carrier in normal rat tissues

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Polymorphisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia.

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Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

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8 July 2018

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy

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8 July 2018

Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741.

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Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects

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8 July 2018

Genetic prognostic and predictive markers in colorectal cancer

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8 July 2018

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

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8 July 2018

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

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Endpoints for assessing drug activity in clinical trials

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8 July 2018

UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma

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8 July 2018

Global analysis of genetic variation in SLCO1B1.

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8 July 2018

Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study

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8 July 2018

Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial

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8 July 2018

Cigarette smoking and irinotecan treatment: pharmacokinetic interaction and effects on neutropenia

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8 July 2018

Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale

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Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

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FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study

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8 July 2018

The effect of leucovorin on the therapeutic index of fluorouracil in cancer patients

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8 July 2018

Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, high-dose leucovorin plus fluorouracil, or sequential methotrexate, fluorouracil, and leucovorin: a randomized trial of the Northern California Oncology Group

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8 July 2018

A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma

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8 July 2018

Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: a homozygote for the SLCO1B1*15 allele

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21 January 2018

Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients

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21 January 2018

Integrated pharmacogenetic prediction of irinotecan pharmacokinetics and toxicity in patients with advanced non-small cell lung cancer

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Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.

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21 January 2018

Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers.

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21 January 2018

Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

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Influence of the organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphisms on irinotecan-pharmacokinetics and clinical outcome of patients with advanced non-small cell lung cancer.

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21 January 2018

UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan

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Pharmacogenetics of SLCO1B1 gene and the impact of *1b and *15 haplotypes on irinotecan disposition in Asian cancer patients

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12 December 2020

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A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24143213

12 December 2020

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A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma

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https://pubmed.ncbi.nlm.nih.gov/24143213

12 December 2020

based on heuristic

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Identifiers

10.1371/JOURNAL.PONE.0077223

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2013PLoSO...877223H

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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