Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention. (Q35022246)

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English	Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.	scientific article

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28 January 2020

Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention (English)

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28 January 2020

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28 January 2020

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Rex Munday

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28 January 2020

Joseph D Paonessa

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Joseph D Paonessa

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28 January 2020

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Yi Ding

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28 January 2020

Kristen L Randall

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28 January 2020

Dayana Argoti

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28 January 2020

Paul Vouros

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12 April 2011

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28 January 2020

Cancer Research

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28 January 2020

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28 January 2020

3904-3911

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28 January 2020

Effect of N-glucuronidation on urinary bladder genotoxicity of 4-aminobiphenyl in male and female mice

1 reference

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8 July 2018

Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues

1 reference

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Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10.

1 reference

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8 July 2018

An improved liquid chromatography-tandem mass spectrometry method for the quantification of 4-aminobiphenyl DNA adducts in urinary bladder cells and tissues.

1 reference

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Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide

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Introducing the "TCDD-inducible AhR-Nrf2 gene battery"

1 reference

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Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species

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5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder.

1 reference

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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

1 reference

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8 July 2018

Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines.

1 reference

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8 July 2018

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

1 reference

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4-Aminobiphenyl N-glucuronidation by liver microsomes: optimization of the reaction conditions and characterization of the UDP-glucuronosyltransferase isoforms

1 reference

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8 July 2018

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

1 reference

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8 July 2018

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

1 reference

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8 July 2018

Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis

1 reference

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8 July 2018

4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene

1 reference

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8 July 2018

UDP-Glucuronosyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107372

8 July 2018

Epidemiology and prevention of bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107372

8 July 2018

Glucuronide conjugates of 4-aminobiphenyl and its N-hydroxy metabolites. pH stability and synthesis by human and dog liver

1 reference

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8 July 2018

Epidemiology of cancer from exposure to arylamines

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DNA adduct measurements and tumor incidence during chronic carcinogen exposure in rodents

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Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis

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8 July 2018

Smoking related carcinogen-DNA adducts in biopsy samples of human urinary bladder: identification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl as a major adduct

1 reference

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The initiation, progress, and diagnosis of dog bladder cancer induced by 4-aminobiphenyl

1 reference

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Isolation of the glucuronic acid conjugate of n-hydroxy-4-aminobiphenyl from dog urine and its mutagenic activity

1 reference

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Tissue- and gender-specific mRNA expression of UDP-glucuronosyltransferases (UGTs) in mice.

1 reference

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25 October 2018

4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice

1 reference

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Nonsmoking-related arylamine exposure and bladder cancer risk

1 reference

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IARC carcinogens reported in cigarette mainstream smoke and their calculated log P values

1 reference

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25 October 2018

Immunohistochemical quantitation of 4-aminobiphenyl-DNA adducts and p53 nuclear overexpression in T1 bladder cancer of smokers and nonsmokers

1 reference

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12 December 2020

based on heuristic

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Carcinogenesis of 4-aminobiphenyl in BALB/cStCrlfC3Hf/Nctr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21487034

12 December 2020

based on heuristic

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Identifiers

10.1158/0008-5472.CAN-11-0396

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28 January 2020

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28 January 2020

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28 January 2020

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