Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model (Q35026344)

5 August 2017

Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model (English)

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5 August 2017

Sanda Despa

1

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5 August 2017

Savita Sharma

2

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5 August 2017

Todd R Harris

3

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5 August 2017

Hua Dong

4

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5 August 2017

Ning Li

5

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5 August 2017

Nipavan Chiamvimonvat

6

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5 August 2017

Heinrich Taegtmeyer

7

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5 August 2017

Kenneth B Margulies

8

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5 August 2017

Bruce D Hammock

9

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5 August 2017

Florin Despa

10

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5 August 2017

21 August 2014

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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

5 August 2017

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5 August 2017

3

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5 August 2017

4

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describes a project that uses

5 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4310392/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

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Amylin deposition in the brain: A second amyloid in Alzheimer disease?

8 July 2018

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Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats

8 July 2018

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Epoxides and soluble epoxide hydrolase in cardiovascular physiology

8 July 2018

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Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats

8 July 2018

1 reference

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Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

8 July 2018

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Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance

8 July 2018

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Treatment with docosahexaenoic acid, but not eicosapentaenoic acid, delays Ca2+-induced mitochondria permeability transition in normal and hypertrophied myocardium

8 July 2018

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Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis

8 July 2018

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Infiltrative cardiovascular diseases: cardiomyopathies that look alike

8 July 2018

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Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy

8 July 2018

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Diabetic cardiomyopathy, causes and effects

8 July 2018

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Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway

8 July 2018

1 reference

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Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process

8 July 2018

1 reference

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Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial

8 July 2018

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Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

8 July 2018

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Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy

8 July 2018

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Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure.

8 July 2018

1 reference

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Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

8 July 2018

1 reference

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Nonischemic heart failure in diabetes mellitus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

8 July 2018

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Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

8 July 2018

1 reference

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Obesity and insulin resistance: effects on cardiac structure, function, and substrate metabolism

8 July 2018

1 reference

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Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase

8 July 2018

1 reference

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Protein misfolding, functional amyloid, and human disease

8 July 2018

1 reference

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From mice to men: insights into the insulin resistance syndromes

8 July 2018

1 reference

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Epoxide hydrolases: their roles and interactions with lipid metabolism

8 July 2018

1 reference

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Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

8 July 2018

1 reference

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Metabolic abnormalities in the diabetic heart

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

8 July 2018

1 reference

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Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines

8 July 2018

1 reference

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Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenases.

8 July 2018

1 reference

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Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Impaired glucose tolerance is associated with increased islet amyloid polypeptide (IAPP) immunoreactivity in pancreatic beta cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

8 July 2018

1 reference

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IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

8 July 2018

1 reference

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Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Mechanisms of [Ca2+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Depressed levels of Ca2+-cycling proteins may underlie sarcoplasmic reticulum dysfunction in the diabetic heart

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310392

Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

25 October 2018

1 reference

12 December 2020

Plasma islet amyloid polypeptide levels in obesity, impaired glucose tolerance and non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Pro islet amyloid polypeptide (ProIAPP) immunoreactivity in the islets of Langerhans

1 reference

12 December 2020

Amylin deposition in the kidney of patients with diabetic nephropathy

1 reference

12 December 2020

Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure

1 reference

12 December 2020

Identifiers

DOI

10.1161/JAHA.114.001015

1 reference

5 August 2017

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5 August 2017

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