Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system. (Q35029006)

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English	Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.	scientific article

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10 December 2019

Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system (English)

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10 December 2019

Consuelo Gajate

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10 December 2019

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10 December 2019

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C Cabaner

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10 December 2019

A Macho

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10 December 2019

M Modolell

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10 December 2019

F Mollinedo

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10 December 2019

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1 June 1999

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10 December 2019

British Journal of Pharmacology

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10 December 2019

127

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10 December 2019

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10 December 2019

813-825

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10 December 2019

Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax.

1 reference

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8 July 2018

Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.

1 reference

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8 July 2018

Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).

1 reference

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8 July 2018

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

1 reference

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8 July 2018

Apoptosis by death factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Mitochondrial control of apoptosis

1 reference

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8 July 2018

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils

1 reference

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8 July 2018

Phase I trial of ilmofosine as a 24 hour infusion weekly

1 reference

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8 July 2018

Apoptosis and the maintenance of homoeostasis in the immune system

1 reference

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8 July 2018

Fas and FasL in the homeostatic regulation of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Early and selective induction of apoptosis in human leukemic cells by the alkyl-lysophospholipid ET-18-OCH3.

1 reference

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8 July 2018

Phase II study of daily oral miltefosine (hexadecylphosphocholine) in advanced colorectal cancer

1 reference

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8 July 2018

Induction of apoptosis in human leukemic cells by the ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. A possible basis for its selective action

1 reference

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8 July 2018

The induction of apoptosis is a common feature of the cytotoxic action of ether-linked glycerophospholipids in human leukemic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

The ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine induces expression of fos and jun proto-oncogenes and activates AP-1 transcription factor in human leukaemic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Phospholipid antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications.

1 reference

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8 July 2018

Antitumoral and other biomedical activities of synthetic ether lysophospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Hexadecylphosphocholine: preclinical and the first clinical results of a new antitumor drug

1 reference

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8 July 2018

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

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8 July 2018

Enhancement of human neutrophil functions by a monoclonal antibody directed against a 19-kDa antigen

1 reference

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8 July 2018

Apoptosis in interleukin-3-dependent haemopoietic cells. Quantification by two flow cytometric methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Hexadecylphosphocholine in the topical treatment of skin metastases in breast cancer patients

1 reference

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8 July 2018

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

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8 July 2018

Alkyllysophospholipid prevents induction of experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

8 July 2018

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566086

25 October 2018

The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1 reference

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1 reference

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25 October 2018

Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of human multiple myeloma-derived cell lines to alkyl-lysophospholipid

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemopurging of peripheral blood-derived progenitor cells by alkyl-lysophospholipid and its effect on haematopoietic rescue after high-dose therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alkyl-lysophospholipid, ET-18-OCH3 synergistically enhances the Merocyanine 540-mediated photoinactivation of leukemia cells: implications for the extracorporeal purging of autologous hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II trial of autologous bone marrow transplantation (ABMT) in acute leukemia with edelfosine purged bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and metabolism of synthetic alkyl analogs of lysophosphatidylcholine in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkyl-lysophospholipid induced suppression of human lymphocyte response to mitogens and selective killing of lymphoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental allergic encephalomyelitis mediated by murine encephalitogenic T cell lines specific for myelin proteolipid apoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SRI 62-834, a cyclic ether analogue of the phospholipid ET-18-OCH3, displays long-lasting beneficial effect in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat. Comparison with cyclosporin and (Val2)-dihydrocyclosporin effe

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical phase I pilot study of the alkyl lysophospholipid derivative ET-18-OCH3

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy of experimental autoimmune encephalomyelitis (EAE): Differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of chronic relapsing experimental allergic encephalomyelitis in the mouse by the alkyl-lysophospholipid ET-18-OCH3

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment results of the thioether lipid ilmofosine in patients with malignant tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylphosphocholines induce apoptosis in HL-60 and U-937 leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10433487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/SJ.BJP.0702606

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10 December 2019

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10 December 2019

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10 December 2019

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