The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis (Q35033140)

5 August 2017

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis (English)

1 reference

5 August 2017

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9

Vicki Huff

1 reference

5 August 2017

Fei Gao

1

1 reference

5 August 2017

Sourindra Maiti

2

1 reference

5 August 2017

Nargis Alam

3

1 reference

5 August 2017

Zhen Zhang

4

1 reference

5 August 2017

Jian Min Deng

5

1 reference

5 August 2017

Richard R Behringer

6

1 reference

5 August 2017

Charlotte Lécureuil

7

1 reference

5 August 2017

Florian Guillou

8

1 reference

5 August 2017

language of work or name

English

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publication date

28 July 2006

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

103

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5 August 2017

32

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5 August 2017

11987-11992

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Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Homozygous inactivation of Sox9 causes complete XY sex reversal in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Functional analysis of Sox8 and Sox9 during sex determination in the mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Requirement of Lim1 for female reproductive tract development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Sox9 induces testis development in XX transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

The human sex-determining gene SRY is a direct target of WT1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Cloning and characterisation of the Sry-related transcription factor gene Sox8.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Endogenous expression of Müllerian inhibiting substance in early postnatal rat sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Enhancement of long-term testosterone secretion and steroidogenic enzyme expression in human Leydig cells by co-culture with human Sertoli cell-enriched preparations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

A male-specific role for SOX9 in vertebrate sex determination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

WT-1 is required for early kidney development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

The evolution of WT1 sequence and expression pattern in the vertebrates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Cell-cell interactions in the testis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Expression of the mouse anti-müllerian hormone gene suggests a role in both male and female sexual differentiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567685

SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

Spectrum of early onset nephrotic syndrome associated with WT1 missense mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

Immunohistochemical evaluation of the cellular localization and ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600994103

Molecular mechanisms of hormone-mediated Müllerian duct regression: involvement of beta-catenin

21 January 2018

1 reference

12 December 2020

Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice

1 reference

12 December 2020

Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development

1 reference

12 December 2020

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development

1 reference

12 December 2020

A comparative study of the differentiation and involution of the mullerian duct and wolffian duct in the male and female fetal mouse

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0600994103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference