Characterization of the usage of the serine metabolic network in human cancer (Q35050220)

6 August 2017

Characterization of the usage of the serine metabolic network in human cancer (English)

1 reference

6 August 2017

Jason W Locasale

4

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author name string

Mahya Mehrmohamadi

series ordinal

1

1 reference

6 August 2017

Xiaojing Liu

series ordinal

2

1 reference

6 August 2017

Alexander A Shestov

series ordinal

3

1 reference

6 August 2017

6 November 2014

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6 August 2017

1 reference

6 August 2017

9

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6 August 2017

4

1 reference

6 August 2017

1507-1519

1 reference

describes a project that uses

6 August 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells

1 reference

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Quantitative flux analysis reveals folate-dependent NADPH production.

8 July 2018

1 reference

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Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

8 July 2018

1 reference

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Development and quantitative evaluation of a high-resolution metabolomics technology

8 July 2018

1 reference

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Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

8 July 2018

1 reference

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The nexus of chromatin regulation and intermediary metabolism.

8 July 2018

1 reference

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Serine, glycine and one-carbon units: cancer metabolism in full circle

8 July 2018

1 reference

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Heterogeneity of tumor-induced gene expression changes in the human metabolic network

8 July 2018

1 reference

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Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis

8 July 2018

1 reference

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

8 July 2018

1 reference

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Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors

8 July 2018

1 reference

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2

8 July 2018

1 reference

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Comprehensive molecular portraits of human breast tumours

8 July 2018

1 reference

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Comprehensive genomic characterization of squamous cell lung cancers

8 July 2018

1 reference

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Comprehensive molecular characterization of human colon and rectal cancer

8 July 2018

1 reference

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Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair.

8 July 2018

1 reference

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A tumour suppressor network relying on the polyamine-hypusine axis

8 July 2018

1 reference

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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

8 July 2018

1 reference

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Resurgence of serine: an often neglected but indispensable amino Acid

8 July 2018

1 reference

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Metabolic modeling of dynamic brain ¹³C NMR multiplet data: concepts and simulations with a two-compartment neuronal-glial model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Inhibition of dUTPase induces synthetic lethality with thymidylate synthase-targeted therapies in non-small cell lung cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Integrated genomic analyses of ovarian carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

GENT: gene expression database of normal and tumor tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Unraveling the biological roles of reactive oxygen species

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Histone methyl transferases and demethylases; can they link metabolism and transcription?

8 July 2018

1 reference

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Metscape: a Cytoscape plug-in for visualizing and interpreting metabolomic data in the context of human metabolic networks

8 July 2018

1 reference

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Reactive oxygen species, cellular redox systems, and apoptosis

8 July 2018

1 reference

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Glutathione redox regulation of in vitro embryogenesis

8 July 2018

1 reference

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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

8 July 2018

1 reference

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KEGG: kyoto encyclopedia of genes and genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317399

On the reliability of (13)C metabolic modeling with two-compartment neuronal-glial models.

25 October 2018

1 reference

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10.1016/J.CELREP.2014.10.026

25 October 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference