Superoxide dismutase: an emerging target for cancer therapeutics (Q35050415)

6 August 2017

Superoxide dismutase: an emerging target for cancer therapeutics (English)

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6 August 2017

Elizabeth A Hileman

1

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6 August 2017

Geetha Achanta

series ordinal

2

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6 August 2017

Peng Huang

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

1 December 2001

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Expert Opinion on Therapeutic Targets

6 August 2017

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6 August 2017

5

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6 August 2017

6

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6 August 2017

697-710

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A threshold concept for cancer therapy

6 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Mitochondrial contributions to cancer cell physiology: redox balance, cell cycle, and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Patterns of 8-hydroxydeoxyguanosine formation in DNA and indications of oxidative stress in rat and human pleural mesothelial cells after exposure to crocidolite asbestos

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Structural origins of bulky oxidative DNA adducts (type II I-compounds) as deduced by oxidation of oligonucleotides of known sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Nitric oxide and mitochondrial respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

8-Nitroxanthine, an adduct derived from 2'-deoxyguanosine or DNA reaction with nitryl chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

DNA damage by nitrite and peroxynitrite: protection by dietary phenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Nitrosation and oxidation in the regulation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Structure and mechanism of copper, zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Evolution of CuZn superoxide dismutase and the Greek key beta-barrel structural motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

A structure-based mechanism for copper-zinc superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Anticancer therapy by overexpression of superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Free Radical Increases in Cancer: Evidence That There Is Not a Real Increase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Persistent oxidative stress in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Oxidative stress and cancer: the role of redox regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

DNA base modifications in chromatin of human cancerous tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Free radicals antioxidant enzymes and lipid peroxidation in different types of leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Expression of CuZn- and Mn-superoxide dismutase in human colorectal neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Antioxidant enzyme activities and oxidative stress in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Antioxidant enzymes are elevated in dimethylbenz[a]anthracene-induced neoplastic murine keratinocytes containing an active rasHa oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Copper/zinc superoxide dismutase, nuclear DNA content, and progression in human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Elevated serum manganese superoxide dismutase in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Antioxidant enzymes in malignant prostate cell lines and in primary cultured prostatic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Kinetic study of O-2 DISMUTATION BY BOVINE SUPEROXIDE DISMUTASE. Evidence for saturation of the catalytic sites by O-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Competitive inhibition of Cu, Zn superoxide dismutase by monovalent anions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

2-methoxyestradiol does not inhibit superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Detection and cytotoxicity of cisplatin-induced superoxide anion in monolayer cultures of a human ovarian cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Oral administration of an estrogen metabolite-induced potentiation of radiation antitumor effects in presence of wild-type p53 in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Induction of mitochondrial manganese superoxide dismutase confers resistance to apoptosis in acute myeloblastic leukaemia cells exposed to etoposide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Reactive oxygen intermediates regulate cellular response to apoptotic stimuli: an hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Role of reactive oxygen species in apoptosis: implications for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.697

21 January 2018

Identifiers

DOI

10.1517/14728222.5.6.697

1 reference

6 August 2017

1 reference