In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor. (Q35057759)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21334234%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor (English)

1 reference

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23 January 2020

1 reference

3

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23 January 2020

Stefano Costanzi

series ordinal

4

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23 January 2020

author name string

Santiago Vilar

series ordinal

1

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23 January 2020

Joel Karpiak

series ordinal

2

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23 January 2020

publication date

19 January 2011

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Journal of Molecular Graphics & Modelling

23 January 2020

published in

1 reference

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23 January 2020

volume

29

1 reference

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23 January 2020

issue

6

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23 January 2020

page(s)

809-817

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21334234%20AND%20SRC:MED&resulttype=core&format=json

Molecular Architecture of G Protein-Coupled Receptors.

23 January 2020

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8 July 2018

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Ligand and structure-based models for the prediction of ligand-receptor affinities and virtual screenings: Development and application to the beta(2)-adrenergic receptor

8 July 2018

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8 July 2018

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Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

8 July 2018

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Structure-based discovery of beta2-adrenergic receptor ligands

8 July 2018

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Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

8 July 2018

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Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.

8 July 2018

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Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

8 July 2018

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Dopamine D2 receptors form higher order oligomers at physiological expression levels

8 July 2018

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On the applicability of GPCR homology models to computer-aided drug discovery: a comparison between in silico and crystal structures of the beta2-adrenergic receptor.

8 July 2018

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Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation

8 July 2018

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

8 July 2018

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6.

8 July 2018

1 reference

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Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor

8 July 2018

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8 July 2018

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Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition

8 July 2018

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8 July 2018

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Computational mapping of the conformational transitions in agonist selective pathways of a G-protein coupled receptor.

8 July 2018

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Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor

25 October 2018

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25 October 2018

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Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor

25 October 2018

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25 October 2018

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10.1016/J.JMGM.2011.01.005

25 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21334234%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21334234%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

21334234

1 reference