Focal adhesion kinase as a potential target in oncology (Q35058125)

6 August 2017

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title

Focal adhesion kinase as a potential target in oncology (English)

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6 August 2017

2

Egle Avizienyte

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6 August 2017

3

Margaret C Frame

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6 August 2017

1

Gordon W McLean

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Expert Opinion on Pharmacotherapy

6 August 2017

published in

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6 August 2017

volume

4

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6 August 2017

issue

2

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6 August 2017

page(s)

227-234

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

6 August 2017

cites work

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21 January 2018

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Signal transduction through integrins: a central role for focal adhesion kinase?

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Focal adhesion kinase and associated proteins

21 January 2018

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Expression of an N-terminally truncated form of human focal adhesion kinase in brain

21 January 2018

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Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

21 January 2018

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pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

21 January 2018

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Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration

21 January 2018

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The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase

21 January 2018

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Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

21 January 2018

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Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

21 January 2018

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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

21 January 2018

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Focal adhesion kinase pp125FAK and the beta 1 integrin subunit are constitutively complexed in HaCaT cells

21 January 2018

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The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

21 January 2018

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ERM proteins in cell adhesion and membrane dynamics

21 January 2018

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

21 January 2018

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Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK

21 January 2018

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PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

21 January 2018

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

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A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

21 January 2018

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The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

21 January 2018

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Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines

21 January 2018

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Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells

21 January 2018

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Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

21 January 2018

1 reference

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Activating SRC mutation in a subset of advanced human colon cancers

21 January 2018

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Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

21 January 2018

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A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

21 January 2018

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Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

21 January 2018

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Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.

21 January 2018

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v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion

21 January 2018

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The focal adhesion kinase--a regulator of cell migration and invasion

21 January 2018

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UCS15A, a non-kinase inhibitor of Src signal transduction

21 January 2018

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UCS15A, a novel small molecule, SH3 domain-mediated protein-protein interaction blocking drug

21 January 2018

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The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.4.2.227

Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes

21 January 2018

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Protein tyrosine kinase inhibitors as novel therapeutic agents

21 January 2018

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From oncogene to drug: development of small molecule tyrosine kinase inhibitors as anti-tumor and anti-angiogenic agents

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14656566.4.2.227

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6 August 2017

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