Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design (Q35058958)

6 August 2017

1 reference

title

Anticancer drugs of tomorrow: apoptotic pathways as targets for drug design (English)

1 reference

6 August 2017

0 references

1

Marek Los

1 reference

6 August 2017

6

Andrzej Mackiewicz

1 reference

6 August 2017

Christof J Burek

2

1 reference

6 August 2017

Christopher Stroh

series ordinal

3

1 reference

6 August 2017

Konrad Benedyk

series ordinal

4

1 reference

6 August 2017

Hubert Hug

series ordinal

5

1 reference

6 August 2017

1 January 2003

1 reference

6 August 2017

1 reference

6 August 2017

8

1 reference

6 August 2017

67-77

1 reference

6 August 2017

2

1 reference

Social controls on cell survival and cell death

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Cell Death in Development

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Proliferation, cell cycle and apoptosis in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis-based therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis in lymphocytic leukemias and lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis and cancer: strategies for integrating programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis as a therapeutic tool in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Serial killers: ordering caspase activation events in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Sensitization of human colon cancer cells to TRAIL-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

TRAIL leads to apoptosis in acute promyelocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Caspases: more than just killers?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Characterization of mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE)

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The Bcl-2 protein family

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The role of the pro-apoptotic Bcl-2 family member bim in physiological cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Double identity for proteins of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

From bench to clinic with apoptosis-based therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

D-RNAi (messenger RNA-antisense DNA interference) as a novel defense system against cancer and viral infections.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The contribution of molecular markers to the prediction of response in the treatment of breast cancer: a review of the literature on HER-2, p53 and BCL-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Bax alpha perturbs T cell development and affects cell cycle entry of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Apoptosis and cell division

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Peptide and Protein Recognition by Designed Molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Protein-protein interfaces: mimics and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Caspase knockouts: matters of life and death.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

RNA interference and small interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Protection against TNF-induced liver parenchymal cell apoptosis during endotoxemia by a novel caspase inhibitor in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Proteasome inhibition in cancer: development of PS-341.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

Rational therapeutic intervention in cancer: kinases as drug targets

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

The role of adenovirus E4orf4 protein in viral replication and cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902563-1

7 January 2021

10.1016/S1359-6446(02)02563-1

Identifiers

DOI

1 reference

release_5ygkpgprhvenpfop5a6mu46qhy

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5ygkpgprhvenpfop5a6mu46qhy

24 November 2022

mapped directly with Wikidata item

1 reference