Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation (Q43583285)

24 November 2017

Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation (English)

1 reference

24 November 2017

1 reference

Stepczynska A

1

1 reference

24 November 2017

Lauber K

2

1 reference

24 November 2017

Engels IH

3

1 reference

24 November 2017

Janssen O

4

1 reference

24 November 2017

Kabelitz D

5

1 reference

24 November 2017

Wesselborg S

6

1 reference

24 November 2017

Schulze-Osthoff K

7

1 reference

24 November 2017

language of work or name

English

0 references

publication date

1 March 2001

1 reference

24 November 2017

1 reference

24 November 2017

20

1 reference

24 November 2017

10

1 reference

24 November 2017

1193-1202

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204221

24 November 2017

0 references

cites work

Control of apoptosis by Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of a Common Pathway of Apoptosis by Staurosporine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

1 reference

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Inhibition of the protein kinase C pathway promotes anti-CD95-induced apoptosis in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Analogs of staurosporine: potential anticancer drugs?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The staurosporine analog, Ro-31-8220, induces apoptosis independently of its ability to inhibit protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of cell death via Fas (CD95, Apo-1) may be associated with but is not dependent on Fas-induced tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cell nucleus and DNA fragmentation are not required for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Apoptosis signaling by death receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204221

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204221

1 reference

Dimensions Publication ID

24 November 2017

0 references

1 reference