Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine (Q35061724)

6 August 2017

title

Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine (English)

1 reference

6 August 2017

Anthony P Young

1

1 reference

6 August 2017

Vahe Bandarian

series ordinal

2

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6 August 2017

publication date

12 July 2013

1 reference

Current Opinion in Chemical Biology

6 August 2017

published in

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6 August 2017

volume

17

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6 August 2017

issue

4

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6 August 2017

page(s)

613-618

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4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate

6 August 2017

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8 July 2018

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8 July 2018

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Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine

8 July 2018

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8 July 2018

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Radicals from S-adenosylmethionine and their application to biosynthesis

8 July 2018

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8 July 2018

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Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea

8 July 2018

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A consensus mechanism for Radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters

8 July 2018

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Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2

8 July 2018

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ENDOR spectroscopy shows that guanine N1 binds to [4Fe-4S] cluster II of the S-adenosylmethionine-dependent enzyme MoaA: mechanistic implications

8 July 2018

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Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4

8 July 2018

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Control of radical chemistry in the AdoMet radical enzymes

8 July 2018

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tRNA's modifications bring order to gene expression

8 July 2018

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Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis

8 July 2018

1 reference

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Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA

8 July 2018

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Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA

8 July 2018

1 reference

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Binding of 5'-GTP to the C-terminal FeS cluster of the radical S-adenosylmethionine enzyme MoaA provides insights into its mechanism

8 July 2018

1 reference

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Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs

8 July 2018

1 reference

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Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid.

8 July 2018

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Post-transcriptional modification in archaeal tRNAs: identities and phylogenetic relations of nucleotides from mesophilic and hyperthermophilic Methanococcales

8 July 2018

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Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

8 July 2018

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Structure of the fluorescent Y base from yeast phenylalanine transfer ribonucleic acid

8 July 2018

1 reference

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Primary structure of wheat germ phenylalanine transfer RNA

8 July 2018

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Origin of the nucleoside Y in yeast tRNAPhe

8 July 2018

1 reference

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Comparative studies on mammalian and yeast phenylalanine transfer ribonucleic acids.

8 July 2018

1 reference

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Structure determination of a new fluorescent tricyclic nucleoside from archaebacterial tRNA.

8 July 2018

1 reference

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Posttranscriptional modification of tRNA in thermophilic archaea (Archaebacteria)

8 July 2018

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Radical SAM enzymes and radical enzymology.

8 July 2018

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In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters

27 September 2018

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Posttranscriptional modification of transfer RNA in the submarine hyperthermophile Pyrolobus fumarii.

27 September 2018

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Biotin synthase mechanism: on the origin of sulphur

27 September 2018

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12 December 2020

The Radical SAM Superfamily

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12 December 2020

Studies on polynucleotides. LXXXII. Yeast phenylalanine transfer ribonucleic acid: partial digestion with ribonuclease T-1 and derivation of the total primary structure

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12 December 2020

S-Adenosylmethionine-dependent reduction of lysine 2,3-aminomutase and observation of the catalytically functional iron-sulfur centers by electron paramagnetic resonance

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12 December 2020

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Identifiers

DOI

1 reference

6 August 2017

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6 August 2017

1 reference