Applications of calorimetric methods to drug discovery and the study of protein interactions (Q35064543)

6 August 2017

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title

Applications of calorimetric methods to drug discovery and the study of protein interactions (English)

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6 August 2017

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Patricia C Weber

1

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6 August 2017

F Raymond Salemme

series ordinal

2

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6 August 2017

publication date

1 February 2003

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Current Opinion in Structural Biology

6 August 2017

published in

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6 August 2017

volume

13

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6 August 2017

issue

1

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6 August 2017

page(s)

115-121

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Direct measurement of protein binding energetics by isothermal titration calorimetry

6 August 2017

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7 January 2021

Heat does not come in different colours: entropy-enthalpy compensation, free energy windows, quantum confinement, pressure perturbation calorimetry, solvation and the multiple causes of heat capacity effects in biomolecular interactions

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7 January 2021

Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery

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7 January 2021

Direct comparison of binding equilibrium, thermodynamic, and rate constants determined by surface- and solution-based biophysical methods

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7 January 2021

High-resolution crystal structures of Erythrina cristagalli lectin in complex with lactose and 2'-alpha-L-fucosyllactose and correlation with thermodynamic binding data

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7 January 2021

Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 protease

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7 January 2021

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes

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7 January 2021

Isothermal titration calorimetry: application to structure-based drug design

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7 January 2021

Interactions defining the specificity between fungal xylanases and the xylanase-inhibiting protein XIP-I from wheat

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7 January 2021

Dominant Thermodynamic Role of the Third Independent Receptor Binding Site in the Receptor-Associated Protein RAP†

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7 January 2021

Interactions between yeast iso-1-cytochrome c and its peroxidase

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7 January 2021

Crowding by trisaccharides and the 2:1 cytochrome c-cytochrome c peroxidase complex

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7 January 2021

Thermodynamics of Ras/effector and Cdc42/effector interactions probed by isothermal titration calorimetry

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7 January 2021

L-phenylalanine binding and domain organization in human phenylalanine hydroxylase: a differential scanning calorimetry study.

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7 January 2021

Unfolding and aggregation during the thermal denaturation of streptokinase

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Unfolding of a leucine zipper is not a simple two-state transition

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7 January 2021

Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies?

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7 January 2021

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Ligand-modulation of the stability of the glucose transporter GLUT 1

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High-density miniaturized thermal shift assays as a general strategy for drug discovery

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7 January 2021

Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteins

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7 January 2021

Exploring the role of bromine at C(10) of (+)-4-[2-[4-(8-chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(R)-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): the discovery of indolocycloheptapyridine inh

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7 January 2021

Influence of Glu-376 --> Gln mutation on enthalpy and heat capacity changes for the binding of slightly altered ligands to medium chain acyl-CoA dehydrogenase

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7 January 2021

Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study.

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7 January 2021

10.1016/S0959-440X(03)00003-4

Identifiers

DOI

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6 August 2017

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