Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators (Q35064907)

6 August 2017

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators (English)

1 reference

6 August 2017

Alice Y Pollitt

8

0 references

Elizabeth Gardiner

Elizabeth E Gardiner

15

0 references

Martine Jandrot-Perrus

Martine Jandrot-Perrus

10

0 references

Robert K. Andrews

Robert K Andrews

13

0 references

Michael W Parker

Michael W Parker

14

0 references

Tracy L Nero

Tracy L Nero

2

0 references

Karlheinz Peter

Karlheinz Peter

16

0 references

author name string

Ulrike Flierl

1

1 reference

6 August 2017

Bock Lim

3

1 reference

6 August 2017

Jane F Arthur

4

1 reference

6 August 2017

Yu Yao

5

1 reference

6 August 2017

Stephanie M Jung

6

1 reference

6 August 2017

Eelo Gitz

7

1 reference

6 August 2017

Maria T K Zaldivia

9

1 reference

6 August 2017

Andreas Schäfer

11

1 reference

6 August 2017

Bernhard Nieswandt

12

1 reference

6 August 2017

language of work or name

English

0 references

publication date

2 February 2015

1 reference

Journal of Experimental Medicine

6 August 2017

1 reference

6 August 2017

212

1 reference

6 August 2017

2

1 reference

6 August 2017

129-137

1 reference

CLEC-2 expression is maintained on activated platelets and on platelet microparticles.

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Oblimersen in combination with temozolomide and albumin-bound paclitaxel in patients with advanced melanoma: a phase I trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

A humanized glycoprotein VI (GPVI) mouse model to assess the antithrombotic efficacies of anti-GPVI agents.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Chemical modification and design of anti-miRNA oligonucleotides.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Pharmacokinetic evaluation of oblimersen sodium for the treatment of chronic lymphocytic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Platelets and innate immunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Single-chain antibodies for the conformation-specific blockade of activated platelet integrin alphaIIbbeta3 designed by subtractive selection from naive human phage libraries

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Toll-like receptor control of the adaptive immune responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Platelet-collagen interaction: is GPVI the central receptor?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

A Toll-like receptor recognizes bacterial DNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Phosphorothioate oligodeoxynucleotides: what is their origin and what is unique about them?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

CpG motifs in bacterial DNA trigger direct B-cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Phosphorothioation of DNA in bacteria by dnd genes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322051

The CD14++CD16+ monocyte subset and monocyte-platelet interactions in patients with ST-elevation myocardial infarction

27 September 2018

1 reference

12 December 2020

Tyrosine Phosphorylation of the Fc Receptor γ-Chain in Collagen-stimulated Platelets

1 reference

12 December 2020

Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice

1 reference

12 December 2020

Evidence of Toll-like receptor molecules on human platelets

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20140391

1 reference

6 August 2017

1 reference

6 August 2017

1 reference