MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. (Q34644199)

3 August 2017

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

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cardiovascular disease

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Eva van Rooij

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

Eric N Olson

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

publication date

19 October 2012

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Nature Reviews Drug Discovery

3 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

volume

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

issue

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

page(s)

860-872

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd3864

12 May 2020

exact match

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cites work

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A Role for miR-145 in Pulmonary Arterial Hypertension

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

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The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis

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MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

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Inhibition of miR-15 protects against cardiac ischemic injury

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microRNA-210 is upregulated in hypoxic cardiomyocytes through Akt- and p53-dependent pathways and exerts cytoprotective effects

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MicroRNAs: target recognition and regulatory functions

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MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

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MicroRNAs can generate thresholds in target gene expression

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Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA

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The impact of microRNAs on protein output

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Widespread changes in protein synthesis induced by microRNAs

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MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.

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Control of stress-dependent cardiac growth and gene expression by a microRNA

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A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

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A cardiac microRNA governs systemic energy homeostasis by regulation of MED13

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A Mediator subunit, MDT-15, integrates regulation of fatty acid metabolism by NHR-49-dependent and -independent pathways in C. elegans

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Mediator MED23 links insulin signaling to the adipogenesis transcription cascade

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An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

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Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

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MicroRNAs 103 and 107 regulate insulin sensitivity

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The Lin28/let-7 axis regulates glucose metabolism

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Flow-Dependent Regulation of Kruppel-Like Factor 2 Is Mediated by MicroRNA-92a

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TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

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31 March 2020

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31 March 2020

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miR-29 is a major regulator of genes associated with pulmonary fibrosis.

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The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microRNA-155 binding

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Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes

31 March 2020

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Regulation of the germinal center response by microRNA-155

31 March 2020

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MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

31 March 2020

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Cardiovascular importance of the microRNA-23/27/24 family

31 March 2020

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Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters

31 March 2020

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MicroRNA-24 regulates vascularity after myocardial infarction

31 March 2020

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miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes

31 March 2020

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Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster

31 March 2020

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The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

31 March 2020

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miR-33 links SREBP-2 induction to repression of sterol transporters

31 March 2020

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MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis

31 March 2020

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MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

31 March 2020

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MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20

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31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23080337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The mechanism of naked DNA uptake and expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23080337

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRD3864

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

release_e4nwgkshfvhnlgb5ncpi3litw4

12 May 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/e4nwgkshfvhnlgb5ncpi3litw4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6813819&resulttype=core&format=json

12 May 2020

1 reference