The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors (Q35069497)

6 August 2017

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors (English)

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6 August 2017

3

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6 August 2017

5

Hans Lehrach

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6 August 2017

Henning Stehr

1

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6 August 2017

Seon-Hi J Jang

2

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6 August 2017

Christoph Wierling

4

1 reference

6 August 2017

Michael Lappe

6

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6 August 2017

Bodo M H Lange

7

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6 August 2017

16 May 2011

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6 August 2017

10

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6 August 2017

54

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https://scigraph.springernature.com/pub.10.1186/1476-4598-10-54

6 August 2017

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Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis

8 July 2018

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Structural and functional restraints on the occurrence of single amino acid variations in human proteins

8 July 2018

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Statistical method on nonrandom clustering with application to somatic mutations in cancer

8 July 2018

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8 July 2018

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A comprehensive catalogue of somatic mutations from a human cancer genome

8 July 2018

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The Universal Protein Resource (UniProt) in 2010

8 July 2018

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Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations

8 July 2018

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Next generation tools for the annotation of human SNPs

8 July 2018

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

8 July 2018

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

8 July 2018

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Functional classification analysis of somatically mutated genes in human breast and colorectal cancers

8 July 2018

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The Catalogue of Somatic Mutations in Cancer (COSMIC)

8 July 2018

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Insights into the oncogenic effects of PIK3CA mutations from the structure of p110alpha/p85alpha

8 July 2018

1 reference

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Prediction of cancer driver mutations in protein kinases

8 July 2018

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Database resources of the National Center for Biotechnology Information

8 July 2018

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The genomic landscapes of human breast and colorectal cancers

8 July 2018

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Patterns of somatic mutation in human cancer genomes

8 July 2018

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Distinguishing cancer-associated missense mutations from common polymorphisms

8 July 2018

1 reference

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The consensus coding sequences of human breast and colorectal cancers

8 July 2018

1 reference

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Predicting the effects of amino acid substitutions on protein function

8 July 2018

1 reference

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PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation

8 July 2018

1 reference

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The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

8 July 2018

1 reference

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Announcing the worldwide Protein Data Bank

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

SIFT: Predicting amino acid changes that affect protein function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Human non-synonymous SNPs: server and survey

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Mutations of the BRAF gene in human cancer

8 July 2018

1 reference

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SNPs, protein structure, and disease.

8 July 2018

1 reference

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dbSNP: the NCBI database of genetic variation

8 July 2018

1 reference

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Activating mutations for the met tyrosine kinase receptor in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

8 July 2018

1 reference

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The multistep nature of cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Dominant forces in protein folding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Inferring the functional effects of mutation through clusters of mutations in homologous proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

The (non)malignancy of cancerous amino acidic substitutions.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

The SAAPdb web resource: a large-scale structural analysis of mutant proteins.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

RAS oncogenes: the first 30 years.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

Protein domain decomposition using a graph-theoretic approach.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3123651

27 September 2018

Identifiers

DOI

10.1186/1476-4598-10-54

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference