New tricks of an old molecule: lifespan regulation by p53 (Q35069567)

6 August 2017

7 references

20 August 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

New tricks of an old molecule: lifespan regulation by p53 (English)

1 reference

6 August 2017

physiological phenomenon

1 reference

20 August 2019

1 reference

28 November 2019

1 reference

11 December 2019

1 reference

18 December 2019

1 reference

19 December 2019

1 reference

20 December 2019

1 reference

Johannes H Bauer

1

1 reference

ORCID Public Data File 2021

author name string

Stephen L Helfand

series ordinal

2

1 reference

6 August 2017

1 October 2006

8 references

6 August 2017

20 August 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

8 references

6 August 2017

20 August 2019

28 November 2019

11 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

5

1 reference

6 August 2017

5

1 reference

6 August 2017

437-440

1 reference

Creative Commons Attribution 2.5 Generic

6 August 2017

1 reference

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

31 July 2022

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Tumor suppression and normal aging in mice with constitutively high p53 activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Differential patterns of apoptosis in response to aging in Drosophila.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Cell death independent of caspases: a review.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

p53: guardian AND suppressor of longevity?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

A Drosophila protein-interaction map centered on cell-cycle regulators

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Diet-gene interactions in p53-deficient mice: insulin-like growth factor-1 as a mechanistic target

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Modulation of mammalian life span by the short isoform of p53.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

A protein interaction map of Drosophila melanogaster

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Diversity in the mechanisms of neuronal cell death.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Drosophila p53 preserves genomic stability by regulating cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

p53 has a direct apoptogenic role at the mitochondria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Human Sir2 and the 'silencing' of p53 activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

p53 mutant mice that display early ageing-associated phenotypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Cancer prevention studies in p53-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Guardian ancestry: fly p53 and damage-inducible apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Identification and characterization of a p53 homologue in Drosophila melanogaster

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Drosophila p53 binds a damage response element at the reaper locus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Caloric intake and aging: mechanisms in rodents and a study in nonhuman primates.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Deletion of Ku86 causes early onset of senescence in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1592233

Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2006.00228.X

Long-lived Drosophila with overexpressed dFOXO in adult fat body

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2006.00228.X

Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2006.00228.X

Aging and p53: getting it straight. A commentary on a recent paper by Gentry and Venkatachalam

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16968311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Between Scylla and Charybdis: p53 links tumor suppression and aging

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16968311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1474-9726.2006.00228.X

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

16968311