Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells (Q35070240)

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Language	Label	Description	Also known as
English	Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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Eric W-F Lam

3

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author name string

John P Alao

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Alexandra V Stavropoulou

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

R Charles Coombes

4

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Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

3 October 2006

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Europe PubMed Central

PubMed publication ID

6 August 2017

Molecular Cancer

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Europe PubMed Central

PubMed publication ID

6 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

40

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Ras, PI(3)K and mTOR signalling controls tumour cell growth

1 reference

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8 July 2018

Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells

1 reference

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The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines

1 reference

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

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8 July 2018

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

1 reference

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells

1 reference

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Inhibition of glycogen synthase kinase 3beta suppresses coxsackievirus-induced cytopathic effect and apoptosis via stabilization of beta-catenin

1 reference

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Histone deacetylase inhibitors and cancer: from cell biology to the clinic

1 reference

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Recent advances in the protein kinase B signaling pathway

1 reference

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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

1 reference

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8 July 2018

Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines

1 reference

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Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

1 reference

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Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

1 reference

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Activation of the PI3K/Akt pathway and chemotherapeutic resistance

1 reference

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Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.

1 reference

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Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

1 reference

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The renaissance of GSK3

1 reference

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GSK3 takes centre stage more than 20 years after its discovery

1 reference

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1 reference

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Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells.

1 reference

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Cellular survival: a play in three Akts

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

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New colorimetric cytotoxicity assay for anticancer-drug screening

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Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity

1 reference

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Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17018141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-5-40

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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