Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact (Q35077713)

6 August 2017

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title

Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact (English)

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6 August 2017

Norman E Sládek

1

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6 August 2017

language of work or name

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1 January 2003

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Journal of Biochemical and Molecular Toxicology

6 August 2017

published in

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6 August 2017

volume

17

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6 August 2017

issue

1

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6 August 2017

page(s)

7-23

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Aldehyde dehydrogenase gene superfamily: the 2000 update.

6 August 2017

cites work

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Suggestions for the nomenclature of human alleles: relevance to ecogenetics, pharmacogenetics and molecular epidemiology

21 January 2018

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Genomic structure of the human cytosolic aldehyde dehydrogenase gene

21 January 2018

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Molecular Cloning, Genomic Organization, and Chromosomal Localization of an Additional Human Aldehyde Dehydrogenase Gene, ALDH6

21 January 2018

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Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13

21 January 2018

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Genomic structure of the human mitochondrial aldehyde dehydrogenase gene

21 January 2018

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Sjögren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene

21 January 2018

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Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH)

21 January 2018

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Human fatty aldehyde dehydrogenase gene (ALDH10): organization and tissue-dependent expression

21 January 2018

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Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family

21 January 2018

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Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison

21 January 2018

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Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family

21 January 2018

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Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism.

21 January 2018

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Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase

21 January 2018

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Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression

21 January 2018

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Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria)

21 January 2018

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Molecular characterization of methylmalonate semialdehyde dehydrogenase deficiency

21 January 2018

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Homology between a human protein and a protein of the green garden pea.

21 January 2018

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An ancient conserved gene expressed in the human inner ear: identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1)

21 January 2018

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cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12

21 January 2018

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Human gamma-aminobutyraldehyde dehydrogenase (ALDH9): cDNA sequence, genomic organization, polymorphism, chromosomal localization, and tissue expression

21 January 2018

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Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition

21 January 2018

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Pharmacogenetics of aldehyde dehydrogenase (ALDH).

21 January 2018

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Human aldehyde dehydrogenase gene family.

21 January 2018

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Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease

21 January 2018

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Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde

21 January 2018

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The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme

21 January 2018

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Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance

21 January 2018

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Aldehyde dehydrogenase content and composition of human liver

21 January 2018

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First purification of the antiquitin protein and demonstration of its enzymatic activity.

21 January 2018

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Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate

21 January 2018

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Expression and localization of human alcohol and aldehyde dehydrogenase enzymes in skin

21 January 2018

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Microsomal aldehyde dehydrogenase is localized to the endoplasmic reticulum via its carboxyl-terminal 35 amino acids

21 January 2018

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Metabolism of retinaldehyde and other aldehydes in soluble extracts of human liver and kidney

21 January 2018

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Expression, purification, and properties of the aldehyde dehydrogenase homologous carboxyl-terminal domain of rat 10-formyltetrahydrofolate dehydrogenase.

21 January 2018

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Identification of the class-3 aldehyde dehydrogenases present in human MCF-7/0 breast adenocarcinoma cells and normal human breast tissue

21 January 2018

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Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells

21 January 2018

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Molecular and biochemical characterization of rat gamma-trimethylaminobutyraldehyde dehydrogenase and evidence for the involvement of human aldehyde dehydrogenase 9 in carnitine biosynthesis

21 January 2018

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Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

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Disruption of histidine catabolism in NEUT2 mice

21 January 2018

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Methanol toxicity and formate oxidation in NEUT2 mice

21 January 2018

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Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases

21 January 2018

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Association of aldehyde dehydrogenase 2 gene polymorphism with multiple oesophageal dysplasia in head and neck cancer patients

21 January 2018

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Deficiency in Mitochondrial Aldehyde Dehydrogenase Increases the Risk for Late-Onset Alzheimer's Disease in the Japanese Population

21 January 2018

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Identification of DNA adducts of acetaldehyde.

21 January 2018

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Gene-environment interaction between an aldehyde dehydrogenase-2 (ALDH2) polymorphism and alcohol consumption for the risk of esophageal cancer

21 January 2018

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Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics

21 January 2018

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Corneal and stomach expression of aldehyde dehydrogenases: from fish to mammals

21 January 2018

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Sjögren-Larsson syndrome is caused by a common mutation in northern European and Swedish patients

21 January 2018

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A common deletion mutation in European patients with Sjögren-Larsson syndrome.

21 January 2018

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A missense mutation in the FALDH gene identified in Sjögren-Larsson syndrome patients originating from the northern part of Sweden.

21 January 2018

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Spectrum of mutations and sequence variants in the FALDH gene in patients with Sjögren-Larsson syndrome

21 January 2018

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The molecular basis of Sjögren-Larsson syndrome: mutation analysis of the fatty aldehyde dehydrogenase gene

21 January 2018

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Mutations in the Delta1-pyrroline 5-carboxylate dehydrogenase gene cause type II hyperprolinemia

21 January 2018

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Prenatal diagnosis of succinic semialdehyde dehydrogenase deficiency: increased accuracy employing DNA, enzyme, and metabolite analyses.

21 January 2018

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Hyperammonemia with reduced ornithine, citrulline, arginine and proline: a new inborn error caused by a mutation in the gene encoding delta(1)-pyrroline-5-carboxylate synthase

21 January 2018

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Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy

21 January 2018

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21 January 2018

The toxicity of methanol

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Identification of cytosolic aldehyde dehydrogenase 1 from non-small cell lung carcinomas as a flavopiridol-binding protein

21 January 2018

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Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid

21 January 2018

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Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells

21 January 2018

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Primary breast tumor levels of suspected molecular determinants of cellular sensitivity to cyclophosphamide, ifosfamide, and certain other anticancer agents as predictors of paired metastatic tumor levels of these determinants. Rational individualiz

21 January 2018

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Cellular levels of aldehyde dehydrogenases (ALDH1A1 and ALDH3A1) as predictors of therapeutic responses to cyclophosphamide-based chemotherapy of breast cancer: a retrospective study. Rational individualization of oxazaphosphorine-based cancer chemo

21 January 2018

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Phenolic antioxidant-induced overexpression of class-3 aldehyde dehydrogenase and oxazaphosphorine-specific resistance.

21 January 2018

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

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Functional antioxidant responsive elements.

21 January 2018

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

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Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

21 January 2018

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

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Regulation of the mammalian cytochrome P1-450 (CYP1A1) gene

21 January 2018

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Drug-metabolizing enzymes in ligand-modulated transcription

21 January 2018

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Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

21 January 2018

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Nrf2 is essential for protection against acute pulmonary injury in mice

21 January 2018

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NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

21 January 2018

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Identification of the enzymatic mechanism of nitroglycerin bioactivation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBT.10057

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6 August 2017

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