A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein (Q35080333)

6 August 2017

A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein (English)

1 reference

6 August 2017

5

Alfred Wittinghofer

1 reference

6 August 2017

6

Klaus Gerwert

1 reference

6 August 2017

3

Yan Suveyzdis

1 reference

6 August 2017

Carsten Kötting

1

0 references

Roger S. Goody

object named as

Roger S Goody

series ordinal

4

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author name string

Marco Blessenohl

series ordinal

2

1 reference

PubMed ID

16968776

6 August 2017

language of work or name

English

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publication date

12 September 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

1 reference

6 August 2017

103

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6 August 2017

38

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6 August 2017

13911-13916

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Proteins in action monitored by time-resolved FTIR spectroscopy

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Theoretical IR spectroscopy based on QM/MM calculations provides changes in charge distribution, bond lengths, and bond angles of the GTP ligand induced by the Ras-protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

ATP hydrolysis in the betaTP and betaDP catalytic sites of F1-ATPase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

GTP hydrolysis mechanism of Ras-like GTPases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Why does the Ras switch "break" by oncogenic mutations?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Heterodimeric GTPase Core of the SRP Targeting Complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Substrate twinning activates the signal recognition particle and its receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

MgF(3)(-) as a transition state analog of phosphoryl transfer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Monitoring the GAP catalyzed H-Ras GTPase reaction at atomic resolution in real time

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Dynamic properties of the Ras switch I region and its importance for binding to effectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

How does GAP catalyze the GTPase reaction of Ras? A computer simulation study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

The mechanism of GTP hydrolysis by Ras probed by Fourier transform infrared spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

The pre-hydrolysis state of p21(ras) in complex with GTP: new insights into the role of water molecules in the GTP hydrolysis reaction of ras-like proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a key role for the beta-phosphate.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Why have mutagenesis studies not located the general base in ras p21.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599887

Enzymatic GTP hydrolysis: insights from an ab initio molecular dynamics study

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

GTPase catalysis by Ras and other G-proteins: insights from Substrate Directed SuperImposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Ras catalyzes GTP hydrolysis by shifting negative charges from gamma- to beta-phosphate as revealed by time-resolved FTIR difference spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Vibrational structure of GDP and GTP bound to RAS: an isotope-edited FTIR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Fourier transform infrared spectroscopy on the Rap.RapGAP reaction, GTPase activation without an arginine finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

The mechanism of Ras GTPase activation by neurofibromin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Chemical confirmation of a pentavalent phosphorane in complex with beta-phosphoglucomutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Quantum chemical modeling of the GTP hydrolysis by the RAS-GAP protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0604128103

Comment on "The Pentacovalent Phosphorus Intermediate of a Phosphoryl Transfer Reaction"

21 January 2018

1 reference

12 December 2020

A chemical synthesis of adenosine 5'-(gamma-32P)triphosphate

1 reference

12 December 2020

A Fourier-transform infrared spectroscopic study of the phosphoserine residues in hen egg phosvitin and ovalbumin

1 reference

12 December 2020

Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction

1 reference

12 December 2020

On the mechanism of guanosine triphosphate hydrolysis in ras p21 proteins

1 reference

12 December 2020

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

1 reference

12 December 2020

Signal transduction via Ras

1 reference

12 December 2020

CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5-TRIPHOSPHATES

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0604128103

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference

PubMed ID

16968776