The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles. (Q35090661)

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5 February 2020

title

The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles (English)

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5 February 2020

2

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5 February 2020

Nicholas J. Santistevan

3

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5 February 2020

author name string

Adam S Cockrell

1

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5 February 2020

Hong Ma

4

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5 February 2020

Tal Kafri

5

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5 February 2020

publication date

24 June 2011

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5 February 2020

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5 February 2020

volume

8

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5 February 2020

page(s)

51

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Notable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector

5 February 2020

cites work

1 reference

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8 July 2018

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8 July 2018

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Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection

8 July 2018

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HIV-1 RNA dimerization: It takes two to tango

8 July 2018

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Integration-deficient lentiviral vectors: a slow coming of age.

8 July 2018

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Rev: beyond nuclear export

8 July 2018

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Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection

8 July 2018

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Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome.

8 July 2018

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Cellular proteins and HIV-1 Rev function

8 July 2018

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A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector

8 July 2018

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HIV-1 reverse transcription initiation: a potential target for novel antivirals?

8 July 2018

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8 July 2018

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Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation

8 July 2018

1 reference

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Selective and nonselective packaging of cellular RNAs in retrovirus particles

8 July 2018

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A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors

8 July 2018

1 reference

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The highly structured encapsidation signal of MuLV RNA is involved in the nuclear export of its unspliced RNA.

8 July 2018

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How retroviruses select their genomes

8 July 2018

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mRNA molecules containing murine leukemia virus packaging signals are encapsidated as dimers

8 July 2018

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Rational development of a HIV‐1 gene therapy vector

8 July 2018

1 reference

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RNA structure and packaging signals in the 5' leader region of the human immunodeficiency virus type 1 genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131246

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131246

Comparison of viral genomic RNA sorting mechanisms in human immunodeficiency virus type 1 (HIV-1), HIV-2, and Moloney murine leukemia virus

8 July 2018

1 reference

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Lentiviral vectors: regulated gene expression

8 July 2018

1 reference

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An intact TAR element and cytoplasmic localization are necessary for efficient packaging of human immunodeficiency virus type 1 genomic RNA.

8 July 2018

1 reference

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Genetic dissociation of the encapsidation and reverse transcription functions in the 5' R region of human immunodeficiency virus type 1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131246

The extended packaging sequence of MoMLV contains a constitutive mRNA nuclear export function

8 July 2018

1 reference

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Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidation

8 July 2018

1 reference

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The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

8 July 2018

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Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.

8 July 2018

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Reduced replication of human immunodeficiency virus type 1 mutants that use reverse transcription primers other than the natural tRNA(3Lys)

8 July 2018

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5' regions of HIV-1 RNAs are not sufficient for encapsidation: implications for the HIV-1 packaging signal

8 July 2018

1 reference

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Identification of a signal in a murine retrovirus that is sufficient for packaging of nonretroviral RNA into virions

8 July 2018

1 reference

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Improved retroviral vectors for gene transfer and expression

8 July 2018

1 reference

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Mutation of the Rev-binding loop in the human immunodeficiency virus 1 leader causes a replication defect characterized by altered RNA trafficking and packaging

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1742-4690-8-51

Rev regulates translation of human immunodeficiency virus type 1 RNAs

21 January 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1742-4690-8-51

Continuous high-titer HIV-1 vector production.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1742-4690-8-51

21 January 2018

Identifiers

DOI

10.1186/1742-4690-8-51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21702950%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

0 references

1 reference

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5 February 2020

PubMed publication ID

21702950

1 reference