Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity (Q35092539)

6 August 2017

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title

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity (English)

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6 August 2017

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S Brian Wilson

1

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6 August 2017

Terry L Delovitch

series ordinal

2

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6 August 2017

publication date

1 March 2003

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Nature Reviews Immunology

6 August 2017

published in

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6 August 2017

volume

3

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6 August 2017

issue

3

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6 August 2017

page(s)

211-222

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The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids

6 August 2017

cites work

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Highly conserved antigen-presenting function of CD1d molecules

31 March 2020

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Predominant use of a particular alpha-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin

31 March 2020

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Oligoclonal Expansion and CD1 Recognition by Human Intestinal Intraepithelial Lymphocytes

31 March 2020

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Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain

31 March 2020

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CD1 recognition by mouse NK1+ T lymphocytes

31 March 2020

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NKT cells: facts, functions and fallacies.

31 March 2020

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The unconventional lifestyle of NKT cells

31 March 2020

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

31 March 2020

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Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining

31 March 2020

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Distinct functional lineages of human V(alpha)24 natural killer T cells

31 March 2020

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The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

31 March 2020

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Tolerance to islet autoantigens in type 1 diabetes

31 March 2020

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Mouse CD1-specific NK1 T cells: development, specificity, and function

31 March 2020

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Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

31 March 2020

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Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes

31 March 2020

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CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of V alpha 24J alpha Q T cells: a feedback mechanism for immune regulation

31 March 2020

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Gene expression in NKT cells: defining a functionally distinct CD1d-restricted T cell subset

31 March 2020

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Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells

31 March 2020

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An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.

31 March 2020

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Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

31 March 2020

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Homeostasis of V alpha 14i NKT cells

31 March 2020

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Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

31 March 2020

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Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

31 March 2020

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CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung

31 March 2020

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Murine natural killer T(NKT) cells [correction of natural killer cells] contribute to the granulomatous reaction caused by mycobacterial cell walls

31 March 2020

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Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer

31 March 2020

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Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity

31 March 2020

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MIP-2 recruits NKT cells to the spleen during tolerance induction

31 March 2020

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Regulation of autoimmune disease by natural killer T cells

31 March 2020

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Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

31 March 2020

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Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

31 March 2020

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A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

31 March 2020

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Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

31 March 2020

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Multiple immuno-regulatory defects in type-1 diabetes

31 March 2020

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Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice

31 March 2020

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CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

31 March 2020

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The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

31 March 2020

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Comparison of the T cell patterns in leprous and cutaneous sarcoid granulomas. Presence of Valpha24-invariant natural killer T cells in T-cell-reactive leprosy together with a highly biased T cell receptor Valpha repertoire

31 March 2020

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Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci

31 March 2020

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Testing the NKT cell hypothesis of human IDDM pathogenesis

31 March 2020

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High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes

31 March 2020

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Do NKT cells control autoimmunity?

31 March 2020

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alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

31 March 2020

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Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

31 March 2020

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IL-7 reverses NK1+ T cell-defective IL-4 production in the non-obese diabetic mouse

31 March 2020

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Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

31 March 2020

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NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

31 March 2020

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Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis

31 March 2020

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Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4

31 March 2020

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Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy

31 March 2020

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Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage

31 March 2020

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Cutting edge: a role for CD1 in the pathogenesis of lupus in NZB/NZW mice

31 March 2020

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NKT-associated markers and perforin in hyperplastic thymuses from patients with Myasthenia gravis

31 March 2020

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Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice

31 March 2020

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Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

31 March 2020

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Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis

31 March 2020

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Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells

31 March 2020

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A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

31 March 2020

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Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways

31 March 2020

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Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

31 March 2020

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Differential tumor surveillance by natural killer (NK) and NKT cells.

31 March 2020

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The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells

31 March 2020

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Sequential production of interferon-gamma by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of alpha -galactosylceramide

31 March 2020

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A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas

31 March 2020

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Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

31 March 2020

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NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

31 March 2020

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Loss of IFN-gamma production by invariant NK T cells in advanced cancer.

31 March 2020

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Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease

31 March 2020

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High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals

31 March 2020

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beta-Cell death during progression to diabetes

31 March 2020

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Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

31 March 2020

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The temporal importance of TNFalpha expression in the development of diabetes

31 March 2020

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

31 March 2020

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The induction of tolerance by dendritic cells that have captured apoptotic cells

31 March 2020

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

31 March 2020

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Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance

31 March 2020

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Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

31 March 2020

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Inhibition of autoimmune diabetes in nonobese diabetic mice by transgenic restoration of H2-E MHC class II expression: additive, but unequal, involvement of multiple APC subtypes

31 March 2020

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

31 March 2020

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Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

31 March 2020

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Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity.

31 March 2020

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Immunobiology of dendritic cells

31 March 2020

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Sensing pathogens and tuning immune responses

31 March 2020

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Reciprocal control of T helper cell and dendritic cell differentiation

31 March 2020

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Dendritic cell lineage, plasticity and cross-regulation

31 March 2020

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Dendritic cells require T cells for functional maturation in vivo

31 March 2020

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CD1-dependent dendritic cell instruction

31 March 2020

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Distinct cytokine profiles of neonatal natural killer T cells after expansion with subsets of dendritic cells

31 March 2020

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Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production

31 March 2020

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CD1-mediated gamma/delta T cell maturation of dendritic cells

31 March 2020

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Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice.

31 March 2020

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CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site.

31 March 2020

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NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

31 March 2020

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Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.

31 March 2020

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Prevention of a Th1 disease by a Th1 cytokine: IL-12 and diabetes in NOD mice

31 March 2020

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Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young no

31 March 2020

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Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

31 March 2020

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Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Human peripheral blood Valpha24+ Vbeta11+ NKT cells expand following administration of alpha-galactosylceramide-pulsed dendritic cells

1 reference

Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells

31 March 2020

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Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs.

31 March 2020

1 reference

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1028

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Dimensions Publication ID

6 August 2017

1029467832

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