Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation (Q35096609)

6 August 2017

title

Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation (English)

1 reference

6 August 2017

Justyna A Janas

1

1 reference

6 August 2017

Linda Van Aelst

series ordinal

2

1 reference

6 August 2017

language of work or name

English

0 references

publication date

2 May 2011

1 reference

Molecular and Cellular Biology

6 August 2017

published in

1 reference

6 August 2017

volume

31

1 reference

6 August 2017

issue

13

1 reference

6 August 2017

page(s)

2552-2565

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Functional proteomics to dissect tyrosine kinase signalling pathways in cancer

6 August 2017

cites work

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Src as a potential therapeutic target in non-small-cell lung cancer.

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

9 July 2018

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Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells

9 July 2018

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The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

9 July 2018

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Phosphoproteomic analysis of Her2/neu signaling and inhibition

9 July 2018

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9 July 2018

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Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis

9 July 2018

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Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases

9 July 2018

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The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

9 July 2018

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9 July 2018

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9 July 2018

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Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.

9 July 2018

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Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

9 July 2018

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Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation.

9 July 2018

1 reference

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Role of Dok-1 and Dok-2 in leukemia suppression

9 July 2018

1 reference

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Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia

9 July 2018

1 reference

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Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth

9 July 2018

1 reference

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Defective downregulation of receptor tyrosine kinases in cancer

9 July 2018

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Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding

9 July 2018

1 reference

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c-Abl phosphorylates Dok1 to promote filopodia during cell spreading

9 July 2018

1 reference

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N-terminal ubiquitination: more protein substrates join in.

9 July 2018

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The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

9 July 2018

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The role of protein tyrosine phosphatase 1B in Ras signaling

9 July 2018

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N-terminal acetyltransferases and sequence requirements for N-terminal acetylation of eukaryotic proteins

9 July 2018

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The protein kinase complement of the human genome

9 July 2018

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9 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

9 July 2018

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A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway

9 July 2018

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Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.

9 July 2018

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p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Oncogenic kinase signalling

9 July 2018

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Synergistic activation of RSK correlates with c-fos induction in MO7e cells stimulated with GM-CSF plus Steel factor

9 July 2018

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Role of Src expression and activation in human cancer

9 July 2018

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Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling

9 July 2018

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p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

9 July 2018

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

9 July 2018

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The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin

9 July 2018

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Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling

9 July 2018

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Characterization of two novel sublines established from a human megakaryoblastic leukemia cell line transfected with p210(BCR-ABL).

9 July 2018

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Src family tyrosine kinases and growth factor signaling

9 July 2018

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Characterization of a novel member of the DOK family that binds and modulates Abl signaling

9 July 2018

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Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation

9 July 2018

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Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration

9 July 2018

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Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.

9 July 2018

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The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R

9 July 2018

1 reference

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FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation

9 July 2018

1 reference

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Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway

9 July 2018

1 reference

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Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression.

9 July 2018

1 reference

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Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins

9 July 2018

1 reference

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Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Oncogenic activation of tyrosine kinases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations

9 July 2018

1 reference

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Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

9 July 2018

1 reference

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Functional role of GTPase-activating protein in cell transformation by pp60v-src

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression

9 July 2018

1 reference

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The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Activation of c-Src in cells bearing v-Crk and its suppression by Csk

9 July 2018

1 reference

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Lentiviral delivery of RNAi in hippocampal neurons

9 July 2018

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Molecular basis of distinct interactions between Dok1 PTB domain and tyrosine-phosphorylated EGF receptor

27 September 2018

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Chronic myelogenous leukemia molecular signature.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3133381

Characterization of a 60-kilodalton substrate of the insulin receptor kinase

27 September 2018

1 reference

12 December 2020

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling

1 reference

12 December 2020

Tyrosine kinases as targets for cancer therapy

1 reference

12 December 2020

Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.05045-11

1 reference

6 August 2017

1 reference

6 August 2017

1 reference