Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion (Q35103303)

6 August 2017

Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion (English)

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6 August 2017

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7

David M Gershenson

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6 August 2017

1

Anil K Sood

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6 August 2017

Jeremy E Coffin

2

1 reference

6 August 2017

Galen B Schneider

3

1 reference

6 August 2017

Mavis S Fletcher

4

1 reference

6 August 2017

Barry R DeYoung

5

1 reference

6 August 2017

Lynn M Gruman

6

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6 August 2017

Michael D Schaller

8

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6 August 2017

Mary J C Hendrix

9

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6 August 2017

language of work or name

English

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publication date

1 October 2004

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The American Journal of Pathology

6 August 2017

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6 August 2017

165

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6 August 2017

1087-1095

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6 August 2017

4

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Focal adhesion kinase: an integrin-linked protein tyrosine kinase

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

FAK signaling in anaplastic astrocytoma and glioblastoma tumors

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Differential regulation of cell motility and invasion by FAK

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

9 July 2018

Cancer statistics, 2003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

The paradoxical expression of maspin in ovarian carcinoma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Sensing the environment: a historical perspective on integrin signal transduction

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Molecular complexity and dynamics of cell-matrix adhesions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Biochemical signals and biological responses elicited by the focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Molecular determinants of ovarian cancer plasticity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

A role for FAK in the Concanavalin A-dependent secretion of matrix metalloproteinase-2 and -9.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

FAK integrates growth-factor and integrin signals to promote cell migration

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Signaling through focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

The focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Control of adhesion-dependent cell survival by focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

The molecular architecture of focal adhesions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Interaction of focal adhesion kinase with cytoskeletal protein talin

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Genetic alterations in epithelial ovarian tumors analyzed by comparative genomic hybridization.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618649

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

27 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Comparative genomic hybridization detects genetic imbalances in primary ovarian carcinomas as correlated with grade of differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

A simple quantitative assay for studying the invasive potential of high and low human metastatic variants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

7 January 2021

Focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Expression of focal adhesion kinase gene and invasive cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963370-6

Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

7 January 2021

1 reference

12 December 2020

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1 reference

12 December 2020

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

1 reference

12 December 2020

The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells

1 reference

12 December 2020

Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK

1 reference

12 December 2020

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

12 December 2020

Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

1 reference

12 December 2020

Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells

1 reference

12 December 2020

Reduced expression of focal adhesion kinase in liver metastases compared with matched primary human colorectal adenocarcinomas

1 reference

12 December 2020

10.1016/S0002-9440(10)63370-6

Identifiers

DOI

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6 August 2017

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6 August 2017

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