Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells (Q35110805)

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English	Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

based on heuristic

inferred from title

phosphorylation

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based on heuristic

inferred from title

author name string

Junyu Ning

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Gang Xi

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

David R Clemmons

3

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

14 June 2011

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Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

152

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Europe PubMed Central

PubMed publication ID

6 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3143-3154

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)

1 reference

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Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway

1 reference

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Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors

1 reference

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Losartan Inhibits Vascular Smooth Muscle Cell Proliferation through Activation of AMP-Activated Protein Kinase

1 reference

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Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways

1 reference

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Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes

1 reference

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PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival

1 reference

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AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation

1 reference

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Diabetes, hyperglycemia and accelerated atherosclerosis: evidence supporting a role for endoplasmic reticulum (ER) stress signaling

1 reference

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AMPK as a metabolic tumor suppressor: control of metabolism and cell growth

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p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment

1 reference

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Energy homeostasis and cancer prevention: the AMP-activated protein kinase

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Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes

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Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy

1 reference

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IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop

1 reference

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Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo

1 reference

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p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 mem

1 reference

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

1 reference

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Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells

1 reference

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Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.

1 reference

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9 July 2018

Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.

1 reference

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The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

1 reference

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Adiponectin actions in the cardiovascular system

1 reference

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AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer

1 reference

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

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Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors

1 reference

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AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells

1 reference

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The AMP-activated protein kinase cascade--a unifying system for energy control

1 reference

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TSC2 mediates cellular energy response to control cell growth and survival

1 reference

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Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

1 reference

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1 reference

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Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells

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Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

1 reference

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AMPK activation inhibits the expression of HIF-1alpha induced by insulin and IGF-1.

1 reference

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1 reference

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Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

1 reference

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1 reference

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Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

1 reference

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Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin and osteopontin bind to insulin-like growth factor (IGF)-binding protein-5 leading to an alteration in IGF-I-stimulated cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673100

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based on heuristic

inferred from PubMed ID database lookup

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673100

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based on heuristic

inferred from PubMed ID database lookup

Activation of cardiac AMP-activated protein kinase by LKB1 expression or chemical hypoxia is blunted by increased Akt activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673100

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Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/21673100

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2011-0155

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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