Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion (Q35112943)

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English	Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion (English)

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Europe PubMed Central

6 August 2017

DNA methylation

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Elin Hall

4

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object named as

Karl Bacos

11

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Clare L Kirkpatrick

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Clare L Kirkpatrick

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object named as

Tina Rönn

10

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object named as

Charlotte Ling

12

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object named as

Lena Eliasson

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author name string

Tasnim Dayeh

1

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Europe PubMed Central

6 August 2017

Petr Volkov

2

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Europe PubMed Central

6 August 2017

Sofia Salö

3

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Europe PubMed Central

6 August 2017

Emma Nilsson

5

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Europe PubMed Central

6 August 2017

Anders H Olsson

6

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Europe PubMed Central

6 August 2017

Claes B Wollheim

8

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

6 March 2014

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

10

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Europe PubMed Central

6 August 2017

e1004160

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Europe PubMed Central

6 August 2017

3

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Europe PubMed Central

6 August 2017

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Creative Commons Attribution 4.0 International

6 March 2014

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3945174/fullTextXML

based on heuristic

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DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets

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9 July 2018

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945174

9 July 2018

Epigenomic plasticity enables human pancreatic α to β cell reprogramming.

1 reference

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9 July 2018

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

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9 July 2018

Extracellular calcium influx activates adenylate cyclase 1 and potentiates insulin secretion in MIN6 cells

1 reference

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9 July 2018

Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes

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Apoptosis in cancer--an update.

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Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes

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Cyclin-dependent kinase inhibitor p21(Waf1): contemporary view on its role in senescence and oncogenesis.

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Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms.

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

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On the presence and role of human gene-body DNA methylation.

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Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes

1 reference

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9 July 2018

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

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DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

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Regulation of calcium in pancreatic α- and β-cells in health and disease

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The worldwide epidemiology of type 2 diabetes mellitus--present and future perspectives

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Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

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Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

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Gene × environment interactions in type 2 diabetes

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Transcriptomes of the major human pancreatic cell types.

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Dietary methyl-consuming compounds and metabolic syndrome

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Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat.

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Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes

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Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles

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Pancreatic alpha cell mass in European subjects with type 2 diabetes

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Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets.

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Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a

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Genomics, type 2 diabetes, and obesity

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Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

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Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

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EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

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Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors

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Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats.

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Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes

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Epigenetics: a molecular link between environmental factors and type 2 diabetes

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Decreased insulin secretion in type 2 diabetes: a problem of cellular mass or function?

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Exenatide blocks JAK1-STAT1 in pancreatic beta cells

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12 December 2020

based on heuristic

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Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1004160

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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